Skip to main content

We narrowed to 434 results for: pme

Showing: 81 - 100 of 434 results
  1. An Integrin Antibody Toolkit from IPI

    Type
    Blog Post
    ...embryonic development, extended-open integrins enable tissue morphogenesis, organ development, and the ...as immune response, tissue repair, and kidney development. Despite their ubiquity and significance, these...all key to basic biomedical research and drug development. Integrin structure and conformational complexity...
  2. Evolution of Brainbow: Using Cre-lox for Multicolor Labeling of Neurons

    Type
    Blog Post
    ... were very time-intensive, necessitating the development of a new technique. In a structure as tightly...lineage tracing; “Zebrabow” was used to trace the development of the corneal epithelium. For scientists interested...interested in neuroscience and development, Brainbow is a valuable tool to mark and follow single cells... Ciruna B, Sanes JR, Luchtman JW, Schier AF. Development. 2013 Jul;140(13):2835-46. doi: 10.1242/dev.094631...
  3. Is this the right place for me? 8 tactics for choosing a lab

    Type
    Blog Post
    ...up to and who doesn’t care about your career development? To get a better idea of whether or not a lab...one that is a true mentor, supporting career development and growth. Have lab alumni gone into both academic...you help or at least observe grant writing? Get equipment quotes? Understand administrative responsibilities...lab help you head for a career in drug/device development? Does the advisor have industry connections such...
  4. Plasmids 101: Repressible Promoters

    Type
    Blog Post
    ...Repressible Binary Systems GAL4/UAS In Drosophila or development studies, you may hear some transcription factor...expression and tracing of gene expression across development. One common binary system is the GAL4/UAS system...place the GAL4 gene downstream of a tissue- or developmental stage-specific promoter and design a UAS reporter...PMCID: PMC3811519.Seo SO, Schmidt-Dannert C. Development of a synthetic cumate-inducible gene expression...
  5. Hot Plasmids: Fall 2025

    Type
    Blog Post
    ...limited compared to other colors. Two recent developments add to this part of the spectrum: PinkyCaMP ...experiments in classroom settings without specialized equipment (Collins & Lau et al., 2024). The method uses ...eliminates the need for expensive reagents and equipment like incubators, micropipettes, and plate readers...analyzed using either "high-tech" or "low-tech" equipment. Reproduced from Collins & Lau et al. (2024) under...
  6. FLEx Technology and Optogenetics: Flipping the switch on gene expression with high spatial and temporal resolution

    Type
    Blog Post
    ...et al., 2006). Despite its relatively recent development, the history of optogenetics begins almost 50...where she worked as a post-doctoral fellow on developmental biology at the École Normale Supérieure de Lyon...Lief, Ofer Yizhar, and Karl Deisseroth. "The development and application of optogenetics." Annual review...Krook-Magnuson. "Specificity, versatility, and continual development: the power of optogenetics for epilepsy research...
  7. Fluorescent Proteins 101: Monitoring Cell Mobility Using Fluorescent Proteins

    Type
    Blog Post
    ...mobility are essential processes during embryonic development. These are required for a growing organism to... follow immune cells in lymphoid organs. The development of cell sorters together with the engineering...cell.     The past 15 years have seen a lot of development surrounding the use of fluorescent proteins and.... "Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas...
  8. Ghanaian Researchers to Receive Plasmid Awards from Addgene and Seeding Labs

    Type
    Blog Post
    ...find and test genes that may play a role in the development of uterine tumors. According to Dr. Bengyella...will be open to researchers who have received equipment through Seeding Labs’ Instrumental Access program...future. Additional Resources Apply to Recieve Equipment through Seeding Labs' Instrumental Access Program...
  9. The CRISPR Software Matchmaker: A New Tool for Choosing the Best CRISPR Software for Your Needs

    Type
    Blog Post
    ...place? How CRISPR innovation affected software development CRISPR, like the miRNA bubble before it, offers...surrounded by a whirlwind of research activity and development since its inaugural year in 2012. That’s just...bubble of innovation (a piñata), and software development has caught up with it. The peer review process... it, it is an obvious place to focus further development toward. Quality control is, however, not a focus...
  10. A Conference By Postdocs For Postdocs: Future of Research

    Type
    Blog Post
    ... creating their own opportunities for career development and networking. Aside from the importance of ...programs they need such as at the Postdoc Career Development Initiative (PCDI) in the Netherlands. There are...This is a free event) Read more Science Career Development posts ...
  11. Lentiviral Vector Guide

    Type
    Guide
    ...understand integration sites have led to the development of multiple genome-wide analysis pipelines to...barcoding libraries . Mouse Modeling Since the development of safer lentiviral vectors, they have been seen...differences. Molecular Therapy — Methods & Clinical Development , 21 , 451–465. https://doi.org/10.1016/j.omtm...sites. Molecular Therapy — Methods & Clinical Development , 20 , 792–800. https://doi.org/10.1016/j.omtm...vectors. Molecular Therapy — Methods & Clinical Development , 3 , 16017. https://doi.org/10.1038/mtm.2016.17...
  12. Three Key Considerations for Precise Neuronal Targeting Using AAV Technologies

    Type
    Blog Post
    ...Understanding the biology behind brain development, learning, and behavior poses many challenges in neuroscience... year, we hosted our first AAV Education and Development workshop aimed at brainstorming strategies for... and guidelines. It was wonderful to see the development of this practical guide by the workshop participants...
  13. New CRISPR Web Resources and #12DaysofCRISPR Recap

    Type
    Blog Post
    ... to make it easy for you to keep up with new developments (and, of course, find plasmids that will be ...CRISPR History provide a great overview of the development of CRISPR into a varied research toolbox, as ...Plasmids and Resources and CRISPR History and Development for Genome Engineering  ...
  14. Plasmids 101: Gene, enhancer, and promoter trapping

    Type
    Blog Post
    ... with. Development-specific genes – if a gene functions at multiple stages in development, its depletion... were observed in the kidneys at a specific developmental stage you could infer that the gene which GFP...
  15. Meet the New Addgene Board Members!

    Type
    Blog Post
    ... viral safety, gene therapy vector development, vaccine development, and assay technologies makes her ...Novartis Institutes for Biomedical Research. Drug development was something Stegmeier has been interested in...
  16. RUBY-Red Siliques

    Type
    Blog Post
    ...these can be challenging and requires specialized equipment. Reporters for studying gene expression have similar...Arabidopsis mutant that can’t set seeds. I study the development of the mutant plants, but the seeds needed for...Willoughby is a graduate student studying plant development and cell-cell communication in the Nimchuk Lab...
  17. Cultivating Community Science at BosLab

    Type
    Blog Post
    ...incubator, a few pipettes, and some home-made equipment. It was humble in comparison to the labs you’d...hub, building up our lab was easy. Most of our equipment has been donated by local companies and BosLab...though, we make sure that everyone gets proper equipment and safety training prior to getting started. ...
  18. Visualizing Translation at the Single Molecule Level

    Type
    Blog Post
    ... key to cellular function, especially during development or stress. With ribosome profiling, researchers...Delayed translation is known to be important in development, and Halstead et al. used TRICK to examine translation...of Drosophila patterning gene oskar. Early in development, the osk-TRICK reporter was double labeled, indicating...
  19. FlipGFP, a novel fluorescence protease reporter to study apoptosis

    Type
    Blog Post
    ...in an array of biological processes including development, the immune system, and cell turnover. Apoptosis...triggered by internal and external signals such as developmental cues and DNA damage. These signals activate ...spatiotemporal dynamics of apoptosis during embryo development. GFP fluorescence increased over time and showed...
Showing: 81 - 100 of 434 results