Announcing the Winners of the 2021 Michael Davidson and Roger Tsien Commemorative Conference Awards
Type
Blog Post
...line, Hep3B. From left to right: Mitotracker Red, GFP for the biosensor, Hoechst, and overlay).
...(DKFZ) who has developed new redox sensitive GFP2 (roGFP2)-based biosensors for live cells. His work focuses..., Pedre Pérez’s biosensor fuses MPST to roGFP2. Because roGFP2 contains two cysteines near the chromophore... anchoring domain), in electroporated in rat hippocampal cultured neurons, imaged 14 days post-transfection...the MPST hydrosulfide can be transferred to the roGFP2 cysteine thiols and change its fluorescence properties... the screen to understand mouse cortical and hippocampal neural microcircuits. “In the longer term, this...