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We narrowed to 310 results for: Gnas

Showing: 121 - 140 of 310 results
  1. Hot Plasmids: Spring 2025

    Type
    Blog Post
    ...somatosensory cortex, while iGluSnFR4s produces larger signal-to-noise ratios in two-photon imaging, making it...single action potential-evoked axonal glutamate signals. Shading denotes SEM. D) Summary of ΔF/F0, Time-to-peak...Waldron Glypicans are important modulators of cell signaling pathways during embryonic development and cancer...
  2. Generating Mouse Models Using CRISPR/Cas9

    Type
    Blog Post
    ...components can be electroporated into the oviduct of pregnant females, a technique called Genome editing via...injection into either an oocyte or into the oviduct of pregnant females (Yoon et al., 2018, Mizuno et al., 2018... it gets exciting – the cell sends out an “SOS” signal and cellular repair mechanisms rush in to repair...
  3. Promega Plasmid Collection

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    Collection
    ... assays are ideal for real-time monitoring of signaling pathways, investigating RNA regulation, tracking...active enzyme and generate a bright luminescent signal in the presence of a substrate. NanoBiT PPI assays...
  4. p53 Pathway

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    Collection
    ...Uncovering the role of p53 splice variants in human malignancy: a clinical perspective. Surget S, Khoury MP,...1905840 . Recruitment of p300/CBP in p53-dependent signal pathways. Avantaggiati ML, Ogryzko V, Gardner K...
  5. Plasmids 101: Modular Cloning Applications and Kits

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    Blog Post
    ...you‘ll need, including sub-cellular localization signals, plant markers, and reporters (Engler et al., 2014...protein degradation on chimeric antigen receptor signaling (Kim et al., 2024). The EMMA Toolkit is another...et al. Degron-Based bioPROTACs for Controlling Signaling in CAR T Cells. Cold Spring Harbor Laboratory,...
  6. Which Fluorescence Microscopy Technique is Best for Me?

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    Blog Post
    ...provides a high contrast image in which a bright signal overlays a perfectly black background. In addition...to more rapid photobleaching and a reduction in signal intensity. 2-Photon microscopes restrict excitation...light-reducing pinhole. By collecting more photons, a higher signal to noise ratio can be achieved (6). Super-resolution...
  7. Antibodies 101: Flow Cytometry

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    Blog Post
    ...the associated fluorochrome, emits a fluorescent signal that is captured by detectors. The strength of ... bind to a primary antibody thus amplifying the signal.       Intracellular protein targets, measured... FITC and that from PE. During compensation the signal arising from a specific fluorochrome is removed...
  8. Rett Syndrome

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    Collection
    ...interacting domain (NID) a nuclear localization signal (not essential for localization) the C - t erminal...C-terminal Anti-MECP2 (D4F3) rabbit antibody from Cell Signalling Technology Additional Resources (Link opens in...
  9. Empty Backbones - Choosing Your Perfect Plasmid Backbone

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    Collection
    ...vector that adds a C-terminal nuclear localization signal pGADCg - Gateway yeast expression vector that adds...adds an N-terminal myristoylation signal GST Protein purification pEBG - N-terminal GST ...
  10. Easing the Protein Purification Process with pCri

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    Blog Post
    ...improves protein solubility and stability. TRX and signal peptide tags help proteins with disulfide bonds...Plasmids designed for these systems may include a signal peptide (SP) that routes the protein through the...
  11. New Norepinephrine Indicators: nLightG and nLightR

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    Blog Post
    ...sensitive than nLightR, both generating a measurable signal after electrical stimulation with a single pulse...pulse, while nLightR gave a measurable signal not at one pulse, but at the second test point, ten pulses...
  12. Supporting Rare Disease Research with BeHeard 2017

    Type
    Blog Post
    ...physicians and scientists.  Although the form of malignant mesothelioma that affects the lining of the lungs... coworkers to test inhibitors of a variety of signaling pathways for their effects on the disease. This...
  13. In Living Color: The Skinny on In Vivo Imaging Tools

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    Blog Post
    ...exactly what iRFPs achieved. Those proteins allowed a signal-to-background ratio in mammalian tissues 20-fold... In addition, PA FPs can improve the achievable signal-to-background ratio, thus, allowing higher resolution...
  14. Multifunctional Neural Fibers: Modulation from Gut to Brain

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    Blog Post
    ...molecular level. The brain is constantly influenced by signals it receives from the entire body, making it difficult...advance our knowledge of brain-visceral organ signaling. The problem  Previously, there were very few...
  15. The Importance of High Titer for AAV Transductions

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    Blog Post
    ...not need to be as high to achieve an observable signal in your experiment, therefore titer may not need...fluorescent proteins required to get a good fluorescent signal. It may not be necessary to concentrate this type...
  16. Hot Plasmids - January 2023

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    Blog Post
    ... Monoclonal antibodies can yield relatively low signal in immunoassays due to only having one binding ...you to use them in parallel to help amplify your signal - giving you the benefit of a polyclonal, with ...
Showing: 121 - 140 of 310 results