We narrowed to 527 results for: MEA;

...enhanced response time allows for more precise measurement of norepinephrine uptake throughout the brain...more sensitive than nLightR, both generating a measurable signal after electrical stimulation with a single...single pulse, while nLightR gave a measurable signal not at one pulse, but at the second test point, ten...

... first need to decide the best way to track or measure the process you’re interested in. Depending on ...examine, i.e. for an enzymatic reaction, you could measure consumption of a substrate OR production of a product...molecule biosensors Addgene has many sensors that measure the concentration of small molecules like arabinose...

...connections with coworkers and doing something meaningful with my career. I can’t pinpoint exactly when...that had never been done at Addgene before. This meant I was responsible for establishing a new report ...present, I thought I would be extremely nervous (I mean I WAS presenting to three department leads, I probably...

...-life balance. It is harder to manage when the measure of work is not just time spent at the desk, but...This requires a focus on deliverables. It does not mean a manager must allow his team to work mostly at ...relationships with clients and colleagues Sometimes this means you have to fire a good performer if they are enough...

...target. Calcineurin reporters allow scientists to measure calcineurin dynamics and can serve as a drug-screening...high throughput screening, calcineurin dynamics measurements, or monitoring in vivo. To overcome these technical...iodine (PI), allowing for calcineurin activity measurements in stressed or aging cell populations. ...

... a form needs to be signed. But the truth is, meaningful progress depends on things being organized, tracked...forward new discoveries and developments.  MTAs also mean that everyone is on the same page as to how the ...becomes available. Our one-time deposit agreement means we only have to work with one tech transfer office...

...increases exponentially with an increase in titer. That means that once you drop below a certain (very high) threshold...concentration to avoid over-diluting, and make sure to remeasure your titer after diluting to confirm. Luke ...Titers: Where do they come from and what do they mean? AAV Vector Quality Control: Going the Extra Mile...

...Understanding Cas9 biophysics enhances HDR We first measured Cas9 dissociation rates and discovered that the... of approximately 6 hours. To our surprise, we measured identical dissociation rates for catalytically...replacement rates of approximately 1%. This is by no means a large number, but it was attained without any ...

...modified Tango beta-arrestin recruitment assay to measure receptor activation for more than 300 GPCRs. In...peroxidase-catalyzed proximity labeling to quantifiably measure GPCR agonist response in vivo (Paek et al., 2017...learn about GPCR signaling, researchers in the meantime have developed GPCRs for chemogenetic studies ...

...Sanjana et al., 2014). It is a dual-vector system, meaning it is typically used in conjunction with a second... be carried over to the gRNA lentiviruses. This means that if you received lentiCas9-blast lentivirus ...(Gi)-mCherry from this virus is cre-dependent, meaning that once injected, the DREADD will only be expressed...

... which often forces scientists to use invasive measures to perform in vivo optogenetic experiments. Intracranial... electrophysiology, a technique that’s used to measure electric current of ion channels in living cells...electrophysiology. All thirty were functional and their measured photocurrent amplitude, wavelength sensitivity...

...imaging applications, smaller affinity reagents means higher resolution. Many of the below are also small...in an ~50kD protein. Minibodies are bispecific, meaning that each scFv can target a different antigen; ...That is the question… or is it? This post isn’t meant to convert anyone to downsize their affinity reagents...

...biorender.com     The modularity of antibodies means that it is relatively easy to physically divide ... vivo.     Of course, the lack of an Fc portion means that most of the common anti-IgG secondary antibodies...monovalent Fab’ or Fab fragments. Higher avidity means that F(ab’)2 fragments may have overall stronger...

...result in unwanted changes at non-target sites. Means to decrease these so-called “off-target effects”...specificity of Cas9 derived from S. aureus. This means you can likely apply similar rational mutations ..., Chen et al. 2017 used single molecule FRET measurements to determine which portions of Cas9 might be...

...researchers had cured 24 mice of their disease. Meanwhile, Hans Clevers and colleagues applied CRISPR to...success rate in clearing misfolded protein levels as measured in the blood. More information is expected soon...difference, then the treatment will not work in a meaningful way. Delivery, especially for systemic approaches...

... highly influenced by this paper. Influence is measured by the number of citations and the context of ...You can also create intersects in your feed which means only papers than contain all of your search terms...by papers published each day, week, or month. A measure of the number of times a paper is shared online...

...initiation site and open circles mark pixels used to measure signal along the dendrite. D) Fluorescence signal...signal as a function of the distance between measured pixel and the soma. The initiation site identified...Figure 4). Figure 4: ONE-GO biosensors measure the formation of Gα-GTP by BRET. The biosensor ...

...specific antibody to the C-terminal five amino acids, meaning the tag could be quite small. However, substance...sequence context.    So, do Schüchner, et al.’s results mean the end of 9E10’s time in the saga of the Myc tag...the variety of formats you can find it in likely mean it will remain an important tool for the foreseeable...

... as real time PCR is a PCR technique used for measuring a starting DNA concentration using PCR. qPCR requires...fluorometer feature built into the thermocycler to measure that fluorescent output. With this fluorescent ...droplet is analyzed by a droplet reader, which measures the fluorescence amplitude of each droplet. The...

... cloning efficiency measurements. We performed additional efficiency measurements using similarly sized...assembly Single insert cloning efficiencies were measured based on the acquisition of antibiotic selectable...