...expressing your gene, especially if you are studying a novel gene, is not always a straightforward process. Rather... of interest, scientists have instead developed novel methods to co-express your gene along with a reporter...more time developing the clever experiments and innovative solutions necessary for advancing the field. ...

...locomotor sensitization and might open new ways for a novel therapeutic approach against drug addiction. Anxiety...illuminated ones (risky). They also prefer to explore novel environments by initially moving along a wall (protected...bright place, driven by their motivation to explore novel environments, rather than being inhibited by fear...

...members are linked to viral susceptibility (mouse adenovirus in mouse; HIV1, West Nile, and Influenza in humans...finding illustrates how the method used to select novel AAV capsid variants could unintentionally limit ...Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP. B capsids." bioRxiv...

...co-founded by Kaspar, acquired by Novartis and rebranded to Novartis Gene Therapies, and Taysha Gene Therapies... in tackling the root cause of Rett Syndrome in novel ways.  Addgene’s MECP2 Plasmid Collection and Resource...

... publish on the health and economic benefits of novel drugs. Commercial Affairs teams make up a large ...for cancer with chemotherapies, or developing innovative mobile phone applications and services that help...the more challenging parts of the job? With fast turnover of projects, pressure to maintain consistently...

...plasmids supporting the evaluation of a diverse set of novel Alzheimer's disease targets....

...using GFP as a scaffold, scientists can design de novo systems using modular components or take advantage...

...inhibited. Recently, we at the Institute for Protein Innovation (IPI), a Boston-based, nonprofit protein research...recombinant antibodies (rAbs) either produced de novo using yeast display technology or produced from ...a science writer at the Institute for Protein Innovation. She writes about all things IPI, from the scientists...

...developed NIR split probes (Tchekanda et al., 2014, Filonov et al., 2013). FRET biosensors were developed based... interactions. Nat Methods 11, 641-644 (2014). Filonov, G.S. & Verkhusha, V.V. A near-infrared BiFC reporter... vivo imaging. Nat Methods 10, 751-754 (2013). Filonov, G.S. et al. Bright and stable near-infrared fluorescent...

...for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives." Proceedings...Academy of Sciences 113.13 (2016): 3509-3514. Tikhonova, Elena B., et al. "A transcription blocker isolated...metalloproteinase: López-Pelegrín, Mar, et al. "A novel mechanism of latency in matrix metalloproteinases...

...Link opens in a new window) Researchers developing novel diagnostics, therapeutics, and vaccines against ...

....2022.07.010 Issa, S. S., Shaimardanova, A. A., Solovyeva, V. V., & Rizvanov, A. A. (2023). Various AAV... Comparison of Gene Delivery to the Kidney by Adenovirus, Adeno-Associated Virus, and Lentiviral Vectors...

... neuroscience research. Institute for Protein Innovation Collection : Antibodies to highly conserved proteins...

...Lentivirus Adeno-associated Virus (AAV) γ-Retrovirus Adenovirus All Viral Plasmids Curated Topics Antibody Plasmid...

...original order. Experimental Disclaimer Due to the novel nature of experiments carried out with our materials...

... rational engineering of biological systems for novel functions. Addgene is working with leading synthetic...

... domain by author. Source: Wikipedia, accessed November 6, 2013. Author: Boghog2 Nuclear receptors are...

...Link opens in a new window) Sztul, E., Chen, P., Casanova, J. E., Cherfils, J., Dacks, J. B., Lambright,...

... exchange, open technologies, and responsible innovation for improvement of sustainable agriculture and...

...vesicular stomatitis virus (VSV; Beier et al., 2011), adenovirus, and adeno-associated virus (AAV), have been ...the California Institute of Technology generated novel AAVs (Chan et al., 2017) that express one of a few...type-specific genetic and optogenetic tools reveal novel hippocampal CA2 circuits. Nat Neurosci 17(2), 269...