Important Considerations When Using AAVs
Type
Blog Post
...University of Manitoba due to their Biosafety Level-2 or 2+.
Please Note: Despite the fact that AAVs themselves...Location (1): What tissue?
Location (2): Where in the tissue/which cell type?
Location (3): Traveling from...in very specific cell populations.
Find Ready-to-Use Retrograde AAV Preps at Addgene
2) Comparison of genetically...long and stable expression (up to 9 months in mice [2]).
Low Immune Response: Compared to other viral vectors...may be sufficient to overcome the transport issues.
2. Failure to plan (for storage) Is planning to fail...Therapy 15.10 (2007): 1740-1743. PubMed PMID: 17882145.
2. Zincarelli, Carmela, et al. "Analysis of AAV serotypes... tropism and axonal transport of AAV serotypes 1, 2, 5, 6, 8 and 9 in the mouse brain." PloS one 8.9 (...