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We narrowed to 614 results for: GAN

Showing: 161 - 180 of 614 results

  1. An Introduction to Adenovirus

    Type
    Blog Post
    ...In April 2022, physicians in Scotland began noticing unusual cases of acute hepatitis in the pediatric... amassed in places around the world, hypotheses began to develop that this illness was caused by either....73.8.6930-6936.1999. PMID: 10400791. Kafri, T., Morgan, D., Krahl, T., Sarvetnick, N., Sherman, L., & ...00379727-84-20714. PMID: 13134217. Schmitz, H., Wigand, R., & Heinrich, W. (1983). Worldwide epidemiology...

  2. 15 Hot Plasmids from 2017

    Type
    Blog Post
    ... using a viral approach Genetically modified organisms like transgenic mice are important tools for understanding...specific to interneurons in mice as well as other organisms, opening the possibility of using these tools ...protein (mCyRFP1). Derived from cyan-excitable organge fluorescent protein (CyOFP1), some of the exciting... a stable monomeric form as determined by the organized smooth endoplasmic reticulum (OSER) assay. A major...coselection, analogous to methods previously used in C. elegans, targets the sodium/potassium pump ATP1A1 in addition...

  3. Designing Your Chalk Talk for the Academic Job Interview

    Type
    Blog Post
    ...grow liver stem cells and liver-like mini-organs or organoids, neither of these can substitute for a liver...talk preparation: Define your research vision. Organize your vision into a chalk talk format. Practice...questions from open ended screens and data collection. Organize your research vision into the chalk talk format...

  4. Twenty Years of Sharing: Addgene's Viral Vector Service

    Type
    Blog Post
    ...number of factors, including the age of the model organism, injection site, and titer. Addgene’s Viral Vector...the University of Pennsylvania’s Vector Core that began in 2018. By the end of 2023, our catalog had grown...respectively, by substrates, light, or engineered ligands (Figure 2). Biosensors, which include calcium and...This prioritization happens for good reasons. We began offering our viral vector service because we realized...

  5. New Acoustic Reporter Genes: Ultrasound Imaging of Gene Expression

    Type
    Blog Post
    ... Fig: 2: Expressing mARGAna in MDA-MB-231 cells. (a) Plasmid diagram of mARGAna. (b) Schematic of the...the general method to create your own mARGAna cell line. (c) Z-projected phase contrast images of GV expressing...Acoustic reporter genes for noninvasive imaging of microorganisms in mammalian hosts. Nature 553, 86–90 (2018...

  6. Mesothelioma - Causes, Symptoms, and Treatment

    Type
    Blog Post
    ...Awareness Organization (ADAO) are working toward such a ban, and the president of the organization, Linda... has spread from where it originated to another organ in the body. Such misdiagnosis and late discovery...tumors from the peritoneum and any other abdominal organs to which it may have spread. Then, the surgeon ...

  7. Data Freedom: The Expansion of Data Sharing in Research Publications

    Type
    Blog Post
    ...Nonetheless, the initial release caused a storm as the organization left open the question of how much data was ...to make the underlying data easily available, organized in a form that can be understood by others, balanced...each individual video. To PLOS’s credit, the organization subsequently clarified what the policy intent...researchers. Yet accurate and comprehensible organization of data is essential for efficient science. ...

  8. Replacing Paper: Tips for Choosing an Electronic lab Notebook

    Type
    Blog Post
    ...our days more effective, and our schedules more organized. From the alarm in the morning, to the daily news...note-taking tools, others using excel sheets or organizing folders in complex ways, there are solutions ...institution, the transition is smooth as all data is organized within an ELN already. Investing some time in ...makes it much easier for lab members to manage and organize their work at every step of the research process...

  9. March for Science

    Type
    Blog Post
    ...rights (2). Less formally, governments are the organizations that make and enforce the rules of the lands...climate change, the safety of genetically modified organisms (GMOs), the absence of a link between vaccines... while their website lists over 200 partner organizations, and 514 satellite marches are scheduled to ...Chronicle of Higher Education: “March for Science” Organizer Says It’s About the Public, Not the Scientists...

  10. Fluorescent Proteins 101: Photoactivatable Fluorescent Proteins

    Type
    Blog Post
    ...are better for whole cell imaging and studying organelle trafficking. Monomeric PA-FPs are usually preferred...involve enhancing optical live imaging of proteins, organelles, and cells. Similar to FPs, PA-FPs allow for ...localization, turnover, and trafficking, as well as organelle trafficking and dynamics (fission, fusion, etc...mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during...

  11. Countdown to Halloween @Addgene

    Type
    Blog Post
    ...couldn’t be more excited! As a small, tight-knit organization we thrive on 3 things: fun, teamwork, and competition...will combine all of these. Addgenies have been organizing Halloween festivities for years – searching our...procrastinating choosing their costume?  As our organization has grown, we continue to have an amazing turnout...

  12. Interview with Bart Newland, Addgene’s Newest Board Member

    Type
    Blog Post
    ...of a lawyer can bring a new perspective to an organization. I'm used to thinking about the downstream results...how to manage them without them paralyzing an organization. I think these are things that I can bring to...that business experience and judgement to the organization and see how I can help. Q: What do you enjoy...

  13. SciComm with the Experts at Science in the News Part 2

    Type
    Blog Post
    ...Set up your own Science by the Pint series and organize evens where scientists can grab a beer and chat...institutional knowledge and continuity - two lead organizers on each program, one junior and one senior.  ...For more info about starting your own SciComm organization and to learn about some of SITN's other initiatives...

  15. Supporting Rare Disease Research with BeHeard 2017

    Type
    Blog Post
    ... are unclear. Dr. Di Schiavi plans on using C. elegans as a model to identify SMN1 interacting partners... of smn1 disruption. As part of his work in C. elegans, Dr. Di Schiavi will use Addgene plasmids to characterize...genes, CRISPR to disrupt their function, and C. elegans overexpression plasmids to upregulate their expression...

  16. In Living Color: The Skinny on In Vivo Imaging Tools

    Type
    Blog Post
    ...peering right through living animals to see their organs – a liver or brain, say, or maybe a tumor. They...for optical labeling and tracking of proteins, organelles, and living cells in a spatiotemporal manner,...  Kendall Morgan...

  17. Genetically-encoded Sparse Cell Labeling - A SPARC of Innovation

    Type
    Blog Post
    ...specifically manipulate a cell type of interest in an organism, all cells of that type are affected. Previous...versatile and can be applied across cell types and organisms by replacing the transcription factor binding ...the PhiC31 recombinase can work in other model organisms including mouse and fish, SPARC is likely generalizable...

  18. Fluorescent Proteins 101: Fluorescent Biosensors

    Type
    Blog Post
    ...interaction, thereby changing the FP’s structural organization and activating the fluorescent signal. Blue ...induces changes in a fluorescent signal based on ligand presence or changing cellular conditions. Other...extracellular molecule? By fusing a biosensor to an organelle-specific targeting signal or a transmembrane domain...

  19. Running for Rare Disease, Running for FOP, Running for AJ

    Type
    Blog Post
    ... Disease that runs on behalf of the National Organization for Rare Disorders (NORD). NORD raises money...responsive to members of the ubiquitous activin ligand family, including Activin A. A commercially developed...We will be collecting donations for IFOPA, an organization dedicated to raising funds and awareness of ...

  20. Fluorescent Biosensors for Measuring Autophagic Flux

    Type
    Blog Post
    ...process by which cytoplasmic material, including organelles, are targeted to lysosomes for degradation. Autophagy...provides limited information about what materials or organelles are being targeted for autophagy. The development...for reporting vacuolar turnover of cytosol and organelles in yeast." Autophagy 4.2 (2008): 205-213. PubMed...
Showing: 161 - 180 of 614 results