...reduced immune effector functions Expression of IgG Monoclonals with Engineered Immune Effector Functions....light-chain DNAs into a single mammalian expression vector A tool kit for rapid cloning and expression of ...1827:313-334. Daniel Christ pComb3 phage display vector system for producing human antibodies Synthetic...Carlos Barbas Variant of the pComb3 phage display vector system for isolation of scFv, diabody and Fab fragment...Methods. 2000 Aug 28;242(1-2):159-81. Carlos Barbas Vector system for expression, dimerisation and detection...antibody fragments in the form of scFvs A simple vector system to improve performance and utilisation of...monoclonal antibodies against zebrafish neural receptors and secreted proteins suitable for wholemount ...

...cellular receptors. The cellular receptor for SARS-CoV-2 and SARS-CoV is hACE2, an angiotensin receptor. Another...Angiotensin Converting Enzyme 2) is the host cell receptor mediating the entry of SARS-CoV and SARS-CoV-2...Cytokines - SARS-CoV-2 infection induces a cytokine storm response in the body. For a full list of cytokines...and open-access SARS-CoV-2 detection assay for laboratory and home testing. Kellner, et al. bioRxiv 2020.06.23.166397... mutants (Timothy Whitehead). SARS-CoV-2 Spike Receptor Binding Domain Deep Mutation Scanning Library ...comprehensive mapping (Jesse Bloom). SARS-CoV-2 Spike Receptor Binding Domain Site-Saturation Mutagenesis Libraries...and Is Blocked by a Clinically Proven Protease Inhibitor . FURIN - Andersen, KG, et al, 2020, Nature Medicine...

...Expression (this is a bicistronic vector rather than a fusion protein vector) ZsGreen1-N1 - Mammalian Expression...93 5.7 10 min Monomer pCS2+mNeonGreen-C Cloning Vector - Mammalian Expression Jump to Top Yellow Protein...5.7 Monomer (A206K) pcDNA3 mCitrine LIC cloning vector (6C) - Mammalian Expression pCS2+8CmCitrine - Zebrafish...Xenopus/C.elegans/Sea urchin pET mCitrine LIC cloning vector (u-mCitrine) - Bacterial Expression mCitrine-N1...562 49 6.5 2.5 hr Monomer pET mOrange LIC cloning vector (u-mOrange) - Bacterial Expression pCS2+8CmOrange... - Mammalian Expression pCS2+mScarlet-C Cloning Vector - Mammalian Expression mScarlet-I 569 593 57 5.4...16 4.5 15 min Monomer pcDNA3 mCherry LIC cloning vector (6B) - Mammalian Expression pLV-mCherry - Mammalian...

... Depositor Collections Allen Institute for Brain Science ...Enhancer AAV plasmids are plasmids which use genomic regulatory sequences — termed enhancers — to drive cell ... AAV delivery. The collection includes the top vectors with the highest specificity and brightness, assessed...pAAV-AiE2563m-minBG-SYFP2-WPRE3-BGHpA AiP1969 AiE2563m SYFP2 Entorhinal area - L2 pyramidal neurons Hippocampal formation...pAAV-AiE2403m-minBG-SYFP2-WPRE3-BGHpA AiP1772 AiE2403m SYFP2 Entorhinal area - L2 pyramidal neurons Hippocampal formation...pAAV-AiE2664m-minBG-SYFP2-WPRE3-BGHpA AiP2107 AiE2664m SYFP2 Entorhinal area - L3 pyramidal neurons Hippocampal formation...pAAV-AiE2664m-minBG-iCre(R297T)-BGHpA AiP20169 AiE2664m Cre Entorhinal area - L3 pyramidal neurons Hippocampal formation...

...interest. Browse Cancer Research Plasmids by Pathway mTOR mTOR is a protein kinase that anchors a signaling network...Cancer Research Broad Target Accelerator Plasmids: Collection of vectors from the Boehm , Hahn , Meyerson...mutated gene in human cancer, is a transcription factor and tumor suppressor. Wnt Coming soon! Kits and...mutant alleles described in the initial Target Accelerator publications, focused on somatic variants found...pan-cancer” analyses. Cancer Pathways ORFs Kit : Set of vectors from the Sabatini & Wood Labs containing cDNAs ... Lab RAS Pathway Clone Collection 2.0 : Set of vectors from the Esposito Lab for use with the Gateway®...permit construction of RAS pathway gene expression vectors for in vitro and in vivo research. TP53 Mutagenesis...

...shRNA CRISPR gRNAs Depositor Collections A modular set of plasmids from a depositor organized by a common...Collections Addgene Plasmid Collections Addgene's repository contains 158,927 plasmids . We've gathered our...our curated plasmid resources, kits, and depositor collections on one page to help you find what you're...looking for a non-plasmid item, browse our entire repository . Plasmid Resources Our curated resources group...common use. Click here to view all collections. Depositor Collection Types CRISPR Fluorescent Proteins Protein... Protein Expression Synthetic Biology Viral Vectors Communities Find a scientific community that has established...Variation on Function (IGVF) Consortium Krüppel-like factors (KLF) Plasmid Resource RESOLUTE Plasmid Collection...

... Viral Vector Packaging Service AAV Serotype Testing AAV Viral Vector Packaging Service: ...available from Addgene's viral service. Control EGFP vectors in various serotypes for serotype testing: AAV1...addition to the standard 100 µL sample size, the vectors listed below are also available as 20 µL. The ...experiments. For more information, see our full AAV inventory or our AAV production page . Note: For a list ...100 µL sized sample, please see our Control AAV Inventory . The catalog ID for the 20 µL sized testing sample...does not have the suffix (for example, AAV1). AAV Vectors for Serotype Testing pAAV-CAG-GFP (Plasmid #37825... eligible AAV plasmids and we’ll make the viral vector prep you need. Or fill out our form to let us know...

...viral vectory packaging service. Browse constructs currently available in viral format.... Viral Vector Packaging...Browse In-Stock AAV Adeno-associated virus (AAV) vectors are safe and useful gene delivery tools that effectively... in small volumes, and ready to ship. All viral vector preps are purified by density centrifugation. Addgene...service. You can choose a transfer plasmid from our repository and request packaging in one of five serotypes...or AAVrg). For more information, visit our Viral Vector Packaging Service overview. Function Chemogenetics...Monster, Brainbow Molecular Tools Tetracycline Transactivators, Affinity Purification, Cell Ablation Monosynaptic...

...Lentiviral reporter vector expressing firefly luciferase. pCMV-FLuc - Retroviral reporter vector expressing firefly...Lentiviral vector expressing destabilized EGFP. Lenti-luciferase-P2A-Neo - Lentiviral reporter vector expressing...permissive cells that express ACE2, the cellular receptor for SARS-CoV-2, in a single round of viral entry...-Luc2-IRES-ZsGreen-W - Lentiviral dual reporter vector expressing firefly luciferase and ZsGreen. NL4-...3 mCherry Luciferase - Lentiviral dual reporter vector expressing mCherry and firefly luciferase. pLentiEGFPdestablized...coronaviruses (184 KB) Addgene Blog Posts Viral Vectors 101: Pseudotyping Antibody Neutralization Response...

...gRNA sequence to direct the dCas9-activator to promoter or regulatory regions of your gene of interest....Empty gRNA Expression Vectors Select a gRNA expression plasmid based on factors such as selectable marker...-FokI Screen Pooled Libraries gRNAs Empty gRNA Vectors gRNAs By Species Mammalian Bacteria Drosophila ...Catalytically dead dCas9 fused to a transcriptional activator peptide can increase transcription of a specific...separate gRNA expression plasmid to target the dCas9-activator to your specific locus. ID Plasmid Gene/Insert...both the gRNA and Cas protein act as all-in-one vectors, but their function is often limited to a single...