Running for Rare Disease, Running for FOP, Running for AJ
Type
Blog Post
... single R206H point mutation on the receptor ACVR1. ACVR1 triggers appropriate bone regeneration in healthy...healthy patients. However, the R206H mutation makes ACVR1 responsive to members of the ubiquitous activin ...Activin A and interferes with inappropriate activin-ACVR1 interactions prevents FOP bone growth in mouse models...FOP in two ways. First, Addgene is distributing ACVR1 Plasmids from a variety of research labs and hopes... cures. We encourage any researchers working on ACVR1 or any of the pathways that impinge upon FOP to ...Treatments with CRIPSR
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