...distinguish highly similar proteins. For example, N-cadherin (cadherin-2) is a postsynaptic cell adhesion protein... By fusing N-cadherin to smFPs the Looger team was able to specifically label N-cadherin in neurons and...map these neuronal networks. For almost three decades, recombinant Adeno-associated virus (AAV) has been...

...Hopefully you know that, if you’re an academic researcher at a nonprofit institution, you can order plasmids...pyranopyridine derivatives." Proceedings of the National Academy of Sciences 113.13 (2016): 3509-3514. Tikhonova...metabolite production." Proceedings of the National Academy of Sciences 113.9 (2016): 2388-2393. Huang, Shijie...antibiotic resistance." Proceedings of the National Academy of Sciences 109.52 (2012): 21408-21413. PUF Assembly... family scaffold." Proceedings of the National Academy of Sciences 108.38 (2011): 15870-15875. See Kendall...

...function through multiple intra-cellular signaling cascades. Optical methods for controlling GPCR activation...control GPCR activation and downstream signaling cascades (reviewed in Abreu & Levitz, 2020), including ...extracellular domain which activates the native signaling cascade of the intracellular part of the receptor, similar... out important branch points along a signaling cascade that may go awry in a disease state.      ... membrane channel. Proceedings of the National Academy of Sciences, 100(24), 13940–13945. https://doi....

...proteins (TniQ, Cas8, Cas7, Cas6) that forms the QCascade DNA-targeting module with the crRNA, 3) a transposase...For the INTEGRATE system to transpose, first the QCascade complex surveys the genome and binds its target...molecule, and inserts it ~50 bp downstream of QCascade’s genomic target site (Fig. 3B). The INTEGRATE ...of RNA-guided transposition with INTEGRATE. The QCascade complex surveys the genome and binds its target...molecule, and inserts it ~50 bp downstream of QCascade’s genomic target site.  T-RL= transposon right-...

...positive perspective on the transition to a post-academic career. This training was “included” with their...training for scientists destined to continue in academia. It seems it’s largely a matter of luck if a student...together with the goal of driving systemic change in academic career readiness training. It's been an honor ...all science training programs. I believe in the academic apprenticeship system as a training ground for...

...were they all to pursue jobs in academia. Certainly funding for academic research and training is getting...get jobs. They are not exposed to the vast non-academia career landscape and there is insufficient (or...Initiative (PCDI) in the Netherlands. There are many academic administrators who are finding ways to provide...

...scientists.  At the same time, he pointed out, academic research has some big problems resulting from ...statistic that only 15% of current postdocs will be academic principal investigators. She also pointed out ...that the PhD and Postdoc advisors only know about academia and alternate training needs to be provided to..., gave examples of how you don’t have to be in academia to make change.  He talked about his own unique...

...study published in Proceedings of the National Academy of Sciences in March, he and his colleagues took...time? Howarth: The Proceedings of the National Academy of Sciences paper [published online on March 17...magnetic cancer cell capture. Fierer et al (Proc Natl Acad Sci U S A. 2014 Mar 17. PubMed) Peptide tag forming...engineering a bacterial adhesin. Zakeri et al (Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):E690-7. Epub 2012...

...out this post if you debating about an academic or non-academic career Learn more about alternative science...sales representative in industry or a postdoc in academia, but knew that, without a doubt, he enjoyed writing...people in.” Are you interested in careers outside academia like science communication? If so, let us know...

...knowledge and groundbreaking discoveries, the world of academia often emphasizes structured methodologies and ...for a successful research career, whether within academia or industry. Albert Einstein once said: “There...poised for groundbreaking discoveries. So, on your academic journey, remember to leave a little space for ...knowledge. Matteo Tardelli authored the book "Beyond Academia: Stories and Strategies for PhDs Making the Leap...

...development of the De-jargonizer.   Academic Phrasebank  The Academic Phrasebank is a resource for phrases...This book has tips for how to write a lot as an academic. If you can’t borrow this book from your library... you directly import papers from web pages and academic databases.  Downloading Mendeley Cite lets you...

...a biotech company. Transitioning an idea from academia to a startup Mike Koeris and fellow co-founders...amazing their idea is. While communication styles in academia and industry vary drastically, he reassures that...venture capital firm with deep ties into the local academic community. However, Mike still could not remove...helpful tips to help transition a project from academia to a biotech startup company? Would you like to...

...’s in 2016 and then working four more years in academia. During my job hunt, I quickly noticed one of ...the biggest differences between applying for an academic position versus an industry position is the on-site...on-site interviewing process. For both of my academic jobs, I interviewed with just the PI of the lab...Resume That Gets Seen Resume writing tips for non-academic science careers Resources on Addgene.org: Sign...

...Victoria, CA Over the decades science has become increasingly restricted to academic and industrial labs...this mutation in the real mutant worm. Like many academic labs, we have the capability to study many different... student at the University of Victoria. After a decade at Microsoft Research working on speech recognition...

...responsible adults in their 30s who have quit their academic science careers in order to head to Ireland and...exchange of information to the public and to other academic labs. Being unable to publish or attend conferences...it very challenging to compete in today’s tough academic or industry job market for biology PhD’s. I was...If you’re thinking about making the switch from academia to entrepreneurship, share your thoughts with ...

...researchers at Amgen, it was stated that only 11% of the academic research in the literature was reproducible by...reproducible, convenient and effective, in both academic circles as well as in industry. The news is good... also explored the barriers to adoption within academic environments to better understand the issues labs...-going maintenance and support.” Besides that, academic institutions tend to think about the long term...

... hello 2020! As we're gearing up to start a new decade, we’re also looking back at the last year of scientific...Addgene. 7. Designing Your Chalk Talk for the Academic Job Interview by Erik Snapp Addgene depositor...breaks down how to prepare a chalk talk for an academic job interview including defining your research...

...Over the past decade there has been a shift in how science is perceived - where once science was only...only seen as a serious academic subject, it is now being appreciated on an aesthetic level as well. Beautiful...forget how to communicate about their work with non-academic people.” Daniel went on to discuss his work: “...

...CRISPR reagents out to academic labs. It is our hope that robust, open academic exploration in this area...with genes knocked out in the insulin signaling cascades in only 4 months compared to a year or greater...

...personnel management?  If you are thinking about a non-academic path, will the PI support this path and help you...answers to your questions. Consider reading Toxic Academic Mentors by @drmellivora, an excellent blog post...interesting Tenure, She Wrote blog. Unfortunately, academic bullies are hard to stop – the best thing to do...