Isolating Genomic Regions of Interest with the CRISPR System
Type
Blog Post
... that binds to the promoter of the growth factor IGF2 open reading frame to relax imprinting (Zhang et...et al., 2017). This upregulates expression of IGF2, a characteristic of many human malignancies. Additionally... identifies miR483 as an epigenetic modulator of IGF2 imprinting in tumors." Oncotarget 8.21 (2017): 34177...