We narrowed to 3 results for: lox2 stop

...presence of Cre, the stop codon is excised, and gene expression proceeds. One popular lox-stop-lox plasmid is...with loxP sites on either side (often called a “lox-stop-lox” or “LSL” cassette) upstream of a gene of interest...is from Tyler Jack's lab: Lox-Stop-Lox TOPO.  Cre-dependent gene knockout – conversely, putting the loxP...canonical sequence. Among these are loxN (GtATACcT), lox2272 (GgATACtT), and lox511 (GtATACAT). These variant...

.... Gene Expression: A stop codon flanked with loxP sites (often called a "lox-STOP-lox" or "LSL" cassette... the absence of Cre. In the presence of Cre, the stop codon is excised, and gene expression proceeds. ... gene expression to physiological levels. In lox-STOP-lox shRNA constructs, Cre expression promotes shRNA...ATAACTTCGTATAgcatacatTATACGAAGTTAT 13 bp inverted repeats + 8 bp spacer (34 bp) lox2272, lox5171, lox511, loxN, lox66/lox71 Dre rox TAACTTTAAATAATgccaATTATTTAAAGTTA...

...recombinase-dependent vector designs used a lox-STOP-lox (LSL) or frt-STOP-frt (FSF) sequence prior to an ATG start...loxp site and one lox2272 site on either end of the transgene. Since loxp and lox2272 can not recombine...are comprised of different sequences (loxp and lox2272) and can not recombine with each other. When Cre...orientation for transcription. Upon recombination one of lox2272 sites will now be sandwiched between 2 loxp sites...binds to either pair of lox sites, let's say the lox2272, that are in the opposite orientation (direction...the loxp site is excised since it is between two lox2272 sites in the same orientation preventing the transgene...