...in correcting an autosomal dominant mutation in MYBPC3 that leads to hypertrophic cardiomyopathy. An adult...adult male with a heterozygous 4 bp deletion in MYBPC3 donated skin, blood and semen samples. Ma et al...repair from the template vs repair from the maternal MYBPC3 allele. Interestingly, they found that the embryos...72.4% of embryos carried two wild-type copies of MYBPC3 (versus 47.4% of untreated controls.) 27.6% of ...germline editing. Nature News mentions that the MYBPC3 gRNA used in the study had few predicted off-target...