How Exercise Purges Stress and Keeps Depression at Bay
Type
Blog Post
...hands on PGC-1a for studies in your own lab, you’ve come to the right place. Get started with PGC-1 plasmids...findings in a recent issue of Cell demonstrate how PGC-1a1, a transcriptional coactivator induced in skeletal...Mice that are genetically modified to produce extra PGC-1a1 only in their skeletal muscle show resistance...interest in sweets.
Further examination of the mck-PGC-1a1 mice found it wasn’t that they were simply immune...brains were protected.
Effects of Activation of the PGC-1a1 Pathway
Gene expression analysis of the animals...degradation. It turns out that activation of the PGC-1a1 pathway increases skeletal muscle expression ...otherwise lead to depression. And there you have it, mck-PGC-1a1 mice, and those who exercise, show resistance...