...recently it hadn’t been used to treat disease postnatally. Now, three papers published concurrently in ...shown CRISPR can treat a genetic disease in a postnatal mouse model, an important proof of concept for... that CRISPR and AAV can be used together for postnatal genome editing in mice. Could this approach work...Bhattacharyya S, Shelton JM, Bassel-Duby R, Olson EN. Postnatal genome editing partially restores dystrophin expression...

...1053 aa/3.2 kb) with AAV vectors for efficient postnatal editing. LbCpf1 and AsCpf1 are 3.7 kb and 3.9 ...

... al. "CRISPR/Cas9-mediated genome editing via postnatal administration of AAV vector cures haemophilia...

...Scientists continue to wrestle with the possibility of postnatal and germline editing, with the International Summit...