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  1. Sonic Hedgehog? Sleeping Beauty? Learn About the Genes Behind Addgene’s Conference Room Names

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    Blog Post
    ...several plasmids that contain SHH, you can find them all here! The most popular SHH plasmid however was deposited... The mammalian hedgehog protein, sonic hedgehog (SHH) was named by a postdoc in Cliff Tabin’s lab who ...inspiration from a comic book his daughter was reading. SHH is involved in the hedgehog signalling pathway, which...key regulator of all bilateral animal development. SHH plays a key role in proper limb and digit formation...formation as well as neural development. Specifically, SHH is a morphogen, a chemical signal that diffuses down...depending on its concentration. Genetic mutations in SHH cause severe health conditions such as nonsyndromic...
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