Genetically-encoded Sparse Cell Labeling - A SPARC of Innovation
Type
Blog Post
...Rodríguez et al., 2011).
Genetics of SPARC
Figure 1: SPARC and SPARC2 use the GAL4-UAS system along with...expression of using the SPARC system. The effector is placed downstream of the rest of the SPARC components and...Isaacman-Beck et al., 2019.
Applications for SPARC
SPARC technology is versatile and can be applied across...Predictive Activity through Recombinase Competition (SPARC), a genetic tool that allows for the labeling of...reliably label any post-mitotic cells in Drosophila. SPARC was developed by Thomas Clandinin’s lab, and incorporates...These sites are target sequences of PhiC31. In the SPARC system, attP sites are located on either side of...integrates an attP site into an attB site. In the SPARC system, PhiC31 irreversibly recombines one of the...