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We narrowed to 242 results for: HTT

Showing: 1 - 10 of 242 results

  1. Viral Vectors 101: Systemic Capsids

    Type
    Blog Post
    Published
    Oct. 12, 2023, 1:15 p.m.
    ...more information on reagents and protocols, visit https://clover.caltech.edu. Figure adapted from Challis... Review of Neuroscience. 2022 Jul 8;45:447-469. https://doi.org/10.1146/annurev-neuro-111020-100834 Challis...in rodents. Nature Protocols;14, 379–414 (2019). https://doi.org/10.1038/s41596-018-0097-3 More resources...Using AAV-PHP.S. eNeuro,9(3), ENEURO.0373-21.2022. https://doi.org/10.1523/ENEURO.0373-21.2022 Brown, D.,...Sequencing. Frontiers in immunology, 12, 730825. https://doi.org/10.3389/fimmu.2021.730825 Campos LJ, Arokiaraj...system. Current Research in Neurobiology, 4, 100086. https://doi.org/10.1016/j.crneur.2023.100086. Challis... Annual Review of Neuroscience, 45(1), 447–469. https://doi.org/10.1146/annurev-neuro-111020-100834 Chan...

  2. Typing CRISPR Systems

    Type
    Blog Post
    Published
    March 18, 2025, 1:15 p.m.
    ... with CRISPR–Cas13. Nature, 550(7675), 280–284. https://doi.org/10.1038/nature24049 Altae-Tran, H., Kannan... deep terascale clustering. Science, 382(6673). https://doi.org/10.1126/science.adi1910 Chylinski, K.,...systems. Nucleic Acids Research, 42(10), 6091–6105. https://doi.org/10.1093/nar/gku241 Cong, L., Ran, F. A...CRISPR/CAS systems. Science, 339(6121), 819–823. https://doi.org/10.1126/science.1231143 Cox, D. B. T.,...with CRISPR-Cas13. Science, 358(6366), 1019–1027. https://doi.org/10.1126/science.aaq0180 Harrington, L....CRISPR-Cas14 enzymes. Science, 362(6416), 839–842. https://doi.org/10.1126/science.aav4294 Hu, C., Myers,...applications. Molecular Cell, 84(3), 463-475.e5. https://doi.org/10.1016/j.molcel.2023.12.034 Kolesnik,...

  3. Viral Vectors 101: AAV Variables That Matter

    Type
    Blog Post
    Published
    June 1, 2023, 1:15 p.m.
    ... Gene Therapy: An Overview. Cells, 12(5), 1–41. https://doi.org/10.3390/cells12050785 Murlidharan, G.,...system. Frontiers in Molecular Neuroscience, 7. https://doi.org/10.3389/fnmol.2014.00076 References and...and 9 in the Mouse Brain. PLOS ONE, 8(9), e76310. https://doi.org/10.1371/journal.pone.0076310 Damdindorj...adeno-associated viral vectors. PLoS ONE, 9(8), 1–10. https://doi.org/10.1371/journal.pone.0106472 de Backer...Hypothalamus. Human Gene Therapy, 21(6), 673–682. https://doi.org/10.1089/hum.2009.169 Dudek, A. M., Pillay...Independent of AAV Receptor. Journal of Virology, 92(7). https://doi.org/10.1128/jvi.02213-17 Favre, D., Blouin...Virus. Journal of Virology, 76(22), 11605–11611. https://doi.org/10.1128/JVI.76.22.11605-11611.2002 Griffin...

  4. Quick Guide to Near-Infrared Fluorescent Proteins

    Type
    Blog Post
    Published
    Oct. 5, 2021, 1:15 p.m.
    ...miRFP703 https://www.addgene.org/79988/ 674 703 90,900 8.6 127 Monomer 394 4.5 37 miRFP709 https://www.addgene.org...mIFP https://www.addgene.org/54620/ 683 705 82,000 8.4 112 Monomer 54 4.5 15  15 miRFP https://www.addgene.org....0 e https://www.addgene.org/54785/ 688 709 98,000 8.1 128 Dimer 108 4.5 8  17 iRFP670 https://www.addgene.org...iRFP682 https://www.addgene.org/45459/ 663 682 90,000 11.1 162 Dimer 490 4.5 105 iRFP702 https://www.addgene.org...iRFP713 https://www.addgene.org/31857/ 690 713 98,000 6.3 100 Dimer 960 4.5 100  19 iRFP720 https://www.addgene.org...emiRFP703 https://www.addgene.org/136558/ 674 703 90,900 8.6 127 Monomer 700 4.5 90 miRFP713 https://www.addgene.org...iRFP713, % d Ref BphP-based FPs miRFP670 https://www.addgene.org/79987/ 642 670 87,400 14.0 198...

  5. Plasmids 101: Modular Cloning Applications and Kits

    Type
    Blog Post
    Published
    May 14, 2024, 1:15 p.m.
    ...Science (PLoS), 18 Feb. 2011, p. e16765. Crossref, https://doi.org/10.1371/journal.pone.0016765. Moore, Simon...Society (ACS), 2 May 2016, pp. 1059–69. Crossref, https://doi.org/10.1021/acssynbio.6b00031. Iverson, Sonya...Society (ACS), 4 Nov. 2015, pp. 99–103. Crossref, https://doi.org/10.1021/acssynbio.5b00124. Obst, Ulrike...Society (ACS), 15 Mar. 2017, pp. 1016–25. Crossref, https://doi.org/10.1021/acssynbio.6b00337. Lee, Michael...Society (ACS), 1 May 2015, pp. 975–86. Crossref, https://doi.org/10.1021/sb500366v. Shaw, William M., et...Society (ACS), 6 Nov. 2023, pp. 3393–405. Crossref, https://doi.org/10.1021/acssynbio.3c00423. Pérez-González...and Business Media LLC, 13 Nov. 2017. Crossref, https://doi.org/10.1186/s12896-017-0393-y. Engler, Carola...

  6. Overcoming the AAV Size Limitation for CRISPR Delivery

    Type
    Blog Post
    Published
    Sept. 16, 2020, 1 p.m.
    ...and its host response. Nat Methods 13:868–874 . https://doi.org/10.1038/nmeth.3993  Cong L, Ran FA, Cox... Using CRISPR/Cas Systems. Science 339:819–823 .https://doi.org/10.1126/science.1231143  Cox DBT, Gootenberg...editing with CRISPR-Cas13. Science 358:1019–1027 . https://doi.org/10.1126/science.aaq0180  Fine EJ, Appleton...using compact expression cassettes. Sci Rep 5: . https://doi.org/10.1038/srep10777  Garneau JE, Dupuis ...bacteriophage and plasmid DNA. Nature 468:67–71 . https://doi.org/10.1038/nature09523  Ibraheim R, Song ...Neisseria meningitidis Cas9 in vivo. Genome Biol 19: . https://doi.org/10.1186/s13059-018-1515-0  Kim E, Koo ...derived from Campylobacter jejuni. Nat Commun 8: . https://doi.org/10.1038/ncomms14500  Levy JM, Yeh W-H,...

  7. Viral Vectors 101: AAV Serotypes and Tissue Tropism

    Type
    Blog Post
    Published
    Jan. 16, 2025, 3:42 p.m.
    ...and 9 in the mouse brain. PloS One, 8(9), e76310. https://doi.org/10.1371/journal.pone.0076310 Bish, L. ...and Rat. Human Gene Therapy, 19(12), 1359–1368. https://doi.org/10.1089/hum.2008.123 Dalkara, D., Byrne...Science Translational Medicine, 5(189), 189ra76. https://doi.org/10.1126/scitranslmed.3005708 Goertsen,...Therapy. Methods & Clinical Development, 26, 331–342. https://doi.org/10.1016/j.omtm.2022.07.010 Issa, S. S....in Gene Therapy: An Overview. Cells, 12(5), 785. https://doi.org/10.3390/cells12050785 Kaludov, N., Brown...Specificity. Journal of Virology, 75(15), 6884–6893. https://doi.org/10.1128/jvi.75.15.6884-6893.2001 Pillay...adeno-associated virus infection. Nature, 530(7588), 108–112. https://doi.org/10.1038/nature16465 Rubin, J. D., Nguyen...

  8. Getting to Know Expansion Microscopy

    Type
    Blog Post
    Published
    June 20, 2023, 1:15 p.m.
    ...conservation of a conoid. PLoS Biology 19:e3001020. https://doi.org/10.1371/journal.pbio.3001020  Chen F, ...2015) Expansion microscopy. Science 347:543–548. https://doi.org/10.1126/science.1260088 Damstra HG, Mohar...Robust Expansion Microscopy (TREx). Elife 11:e73775. https://doi.org/10.7554/elife.73775  Dani A, Huang B, ...Chemical Synapses in the Brain. Neuron 68:843–856. https://doi.org/10.1016/j.neuron.2010.11.021  Gambarotto...expansion microscopy (U-ExM). Nat Methods 16:71–74. https://doi.org/10.1038/s41592-018-0238-1  Klimas A, Gallagher... for expansion microscopy. Nat Biotechnol 1–12. https://doi.org/10.1038/s41587-022-01546-1  Mikhaylova...using anti-tubulin nanobodies. Nat Commun 6:7933. https://doi.org/10.1038/ncomms8933  M’Saad O, Bewersdorf...

  9. An “elegans” Approach to Better CRISPR/Cas9 Editing Efficiency

    Type
    Blog Post
    Published
    Dec. 17, 2020, 1:30 p.m.
    ... Caenorhabditis elegans. Genetics 198:837–846 . https://doi.org/10.1534/genetics.114.169730 Bottcher R...Drosophila cells. Nucleic Acids Research 42:e89–e89 . https://doi.org/10.1093/nar/gku289 Chen C, Fenk LA, de...recombination. Nucleic Acids Research 41:e193–e193 . https://doi.org/10.1093/nar/gkt805 Dickinson DJ, Pani ...Drug Selection Cassette. Genetics 200:1035–1049 . https://doi.org/10.1534/genetics.115.178335 Dokshin GA... Caenorhabditis elegans. Genetics 210:781–787 . https://doi.org/10.1534/genetics.118.301532 Ebbing A, ...alternative gene editing system for AT-rich sequences https://doi.org/10.17912/W2237D Farboud B, Severson AF...Editing Using CRISPR-Cas9. Genetics 211:431–457 . https://doi.org/10.1534/genetics.118.301775 Ghanta KS,...

  10. Plasmids 101: Expressing shRNAs for RNA Interference

    Type
    Blog Post
    Published
    June 17, 2025, 1:15 p.m.
    ...null,"href":"https://www.addgene.org/collections/mammalianrnai/","href_with_scheme":"https://www.addgene.org...D. P. (2004). MicroRNAs. Cell, 116(2), 281–297. https://doi.org/10.1016/s0092-8674(04)00045-5 De Rie, ...and mouse. Nature Biotechnology, 35(9), 872–878. https://doi.org/10.1038/nbt.3947 Fire, A., Xu, S., Montgomery...Caenorhabditis elegans. Nature, 391(6669), 806–811. https://doi.org/10.1038/35888  Iwakawa, H., & Tomari, ...silencing complex. Molecular Cell, 82(1), 30–43. https://doi.org/10.1016/j.molcel.2021.11.026 Kilikevicius...silencing. Nucleic Acids Research, 50(2), 617–634. https://doi.org/10.1093/nar/gkab1256 Lee, Y., Kim, M.,...polymerase II. The EMBO Journal, 23(20), 4051–4060. https://doi.org/10.1038/sj.emboj.7600385 McIntyre, G. ...
Showing: 1 - 10 of 242 results