...monitor protein and cell ageing, as the spectrum shift occurs during Timer protein life due to a form of...read the Addgene interview with Mark Howarth. Shining a light on channelrhodopsins – Chronos & Chrimson...spectral peak at 590 nm, which is 45 nm more red-shifted compared to other variants. The group further optimized...functional GFP, and the cells will turn green. Mashiko et al., Sci Rep 2013 Nov 27; 3:3355. Rinehart...TALEN assembly and activity? The laboratory of Takashi Yamamoto has created a complete TALEN assembly ...

...and watch it now! (Bonus: Tim kindly offered to finishing answering all submitted questions via blog post... the next few weeks.)  Finally, Addgenies love sunshine and warm weather - check out our Instagram all...endeavors - in between some much-deserved vacations, sunshine, and beach trips, of course.    *not me, though...

... FACS machine after a single use. So how about washing and reusing pipette tips in a high-throughput and...example, offers automated, benchtop, high throughput washing devices that are compatible with a variety of pipette...incentives (for example, by grant agencies), we can shift toward a more sustainable one. The math on this ...

...of the method. One observation was an inverse relationship between deletion size and frequency [3]. There...coding sequences often result in loss-of-function frameshift mutations. However these may require restriction...genomic landscape may be surveyed in unprecedented fashion. Targeted deletions are just one of many available...

...muscular atrophy patients. Noushin Nabavi - Peritoneal Mesothelioma  Noushin Nabavi is a Postdoctoral Fellow...diagnostic tools and animals models of the disease in partnership with Taconic Biosciences. The study of peritoneal...

...repository in 2023.  In June, we announced a new partnership with the Institute for Protein Innovation (IPI...we’re pleased to announce that we are now able to ship rabies plasmids in our repository to international...through active conversation and collaboration.  Wishing you a healthy, productive, and thriving 2024, mirroring...

...Expanding your network of relationships early and often is the most effective tactic a scientist in training...result of existing professional (and personal) relationships. However, most job seekers will and should apply...after the academic bench. Utilizing existing relationships as part of the job application process can dramatically...

...person, and helps improve your interpersonal relationships with people you’re collaborating with remotely...like something out of your nightmares, shared ownership of materials produced from your collaboration ...the project. The state of research is constantly shifting, and long-distance collaborations are becoming...

...awesome. The process of writing, editing, and publishing blog posts runs its course more quickly than ...supervisors warned me, the swift gratification of publishing posts can be addicting. Even more satisfying,...always thoroughly enjoyed: travel. I’m actually finishing up this post on a plane back to Boston from Kentucky...

...deaminase from sea lamprey fused to Cas9 nickase (Nishida et al., 2016). Target-AID acts similarly but not...efficiency but higher indel formation than BE2 Nishida et al., 2016 Target-AID   Edits 3-5 base window...685. https://doi.org/10.1038/s41587-022-01533-6 Nishida, K., Arazoe, T., Yachie, N., Banno, S., Kakimoto...Mochizuki, M., Miyabe, A., Araki, M., Hara, K. Y., Shimatani, Z., & Kondo, A. (2016). Targeted nucleotide editing...