We narrowed to 466 results for: SHI

...deaminase from sea lamprey fused to Cas9 nickase (Nishida et al., 2016). Target-AID acts similarly but not...efficiency but higher indel formation than BE2 Nishida et al., 2016 Target-AID   Edits 3-5 base window...685. https://doi.org/10.1038/s41587-022-01533-6 Nishida, K., Arazoe, T., Yachie, N., Banno, S., Kakimoto...Mochizuki, M., Miyabe, A., Araki, M., Hara, K. Y., Shimatani, Z., & Kondo, A. (2016). Targeted nucleotide editing...

...person, and helps improve your interpersonal relationships with people you’re collaborating with remotely...like something out of your nightmares, shared ownership of materials produced from your collaboration ...the project. The state of research is constantly shifting, and long-distance collaborations are becoming...

...awesome. The process of writing, editing, and publishing blog posts runs its course more quickly than ...supervisors warned me, the swift gratification of publishing posts can be addicting. Even more satisfying,...always thoroughly enjoyed: travel. I’m actually finishing up this post on a plane back to Boston from Kentucky...

...whether I’m working with a talented journalist to shine light on living as a scientist in Beijing, talking...emotional investment and following cause-and-effect relationships are all things almost all of us are programmed...Interviewee: “I did the most work for a paper we were publishing, but when it came time to add author details ...

...new FP. Their aim - to red-shift the boundaries of FP technology by shifting the emission maxima toward...APOBEC-Cas9n-UGI-mediated activity edits out a frame-shift mutation within the mCherry reporter. Quantification...

...FDA-approved). This is a big job, but under the leadership of Nevan Krogan at UCSF we’ve brought together...line, with a row of FedEx envelopes waiting to be shipped out of the Krogan lab at UCSF. Our team members...Foussard, and Dave Gordon) have been quite busy shipping and sending plasmids to all who request them -...

... for clear communication, fair credit through authorship, and acceptance of a diversity of work styles...stress the fact that “miscommunication, a lack of leadership, and inappropriate tools or writing approaches...that was probably lost during these weird times of shift working and social distancing. The take home message...

...returned the MTA, Addgene can move forward with shipping the material to the requestor.  Why the MTA?  ...certainly frustrating to find out your plasmid hasn’t shipped because a form needs to be signed. But the truth... And that’s where MTAs, and similar agreements, shine.  These types of agreements allow for centralized...

...jumped at the chance. Here was an opportunity to see Shinya Yamanaka celebrate the tenth anniversary of his...clinical trial with iPSCs with his collaborator Takahashi in 2014 – just 8 years after the OSKM paper – ...panel of thought leaders in the field--including Shinya Yamanaka, George Q. Daley, Christine Mummery, Lorenz...

...however, it requires high doses. Requests have shifted toward the more efficient AAV-PHP.eB, developed...Evolutionary tree depicting the phylogenetic relationship of common research species. Among these species..., Kim, H.M., Rajendran, P.S., Tompkins, J.D., Shivkumar, K., Deverman, B.E., Gradinaru V. Systemic AAV...0799-7 Lawler, A. J., Ramamurthy, E., Brown, A. R., Shin, N., Kim, Y., Toong, N., Kaplow, I. M., Wirthlin....017 Matsuzaki, Y., Konno, A., Mochizuki, R., Shinohara, Y., Nitta, K., Okada, Y., & Hirai, H. (2018)....