Negative Can Be Positive: Open AAV Data with Addgene
Type
Blog Post
Published
Sept. 6, 2022, 1:15 p.m.
...adjacent areas impacted the experiments we wanted to perform. It required a great deal of time and effort to... reformulating our AAV construct to optimize performance in our system and yet none of that data was published...packaging viral particles (6), can influence vector performance. Open science initiatives, like Addgene’s Data... to help scientists understand how our vectors perform in various experimental settings. It is a curated...low-magnification images demonstrating vector performance) will be assigned citable DOIs through DataCite... broadening the knowledge base of AAV vector performance in various brain regions and cell types.
Power...potentially available to evaluate AAV vector performance. Yet, most of the technical data needed to replicate...