We narrowed to 222 results for: Mac

...toolkit for epitope tagging in neurons Harold MacGillavry’s lab developed a CRISPR-based toolkit for targeted...

..., Lianna Swanson, and researcher at Sanofi Pharmaceuticals. This post highlights a rare disease, Fibrodysplasia...

...The Addgene lab often works as a very well-oiled machine and this post was no exception - the rest of the...

... notebooks (ELNs) have gained traction with pharmaceutical companies, academic labs have been slower to...

...study the expression of an unknown protein in macrophages/monocytes using lentiviral expression vectors...

... vivo brain microdialysis: advances in neuropsychopharmacology and drug discovery." Expert opinion on ...

...substrate to produce bioluminescence. Substrate pharmacokinetics and biodistribution therefore introduce additional...

... you’re interested in (i.e. biotechnology, pharmaceuticals, etc.) Do their jobs sound interesting? Is ...

...well known and, as a result, a target of many pharmaceutical drugs, there is still only a partial understanding...

...Tools with Therapeutic Utility. Annual Review of Pharmacology and Toxicology 55:399–417 . https://doi.org/...

...replication within a plasmid by recruiting replication machinery proteins Antibiotic Resistance Gene Allows for...

...Endophytes as sources of antibiotic” Biochemical Pharmacology 2017 Jun 15;134:1-17. PubMed PMID: 27984002....

...even compared his "memory" gene codes to a Turing machine (also discussed in the book). These synthetic biologists...

...illustration above) and bribed the guys in the hospital machine shop with coffee and donuts to cut the pieces of...

...breaks Bactericidal 5-100 ug/mL Erythromycin macrolide Blocks 50S ribosomal subunit; inhibits aminoacyl...

...pAAV CD68-hM4D(Gi)-mCherry (CD68 is a  microglia/macrophage promoter) 121539  AAV5  pOTTC1596 - pAAV SYN1...

...References and resources References Al-Allaf FA, Tolmachov OE, Zambetti LP, Tchetchelnitski V, Mehmet H (...

... database. Through a series of simulations and machine learning, they created a classifier that predicts...

...specific and much faster than any genetic or pharmacological manipulations on cells, and has potential use...

...meetings or that there’s some correct level of intimacy that creates the magic of a safe space. No matter...

...Therapeutics, which was acquired by Ultragenyx Pharmaceutical in 2017. As one of the original employees at...

...transfect the ‘helper’ plasmids (viral packaging machinery) along with the viral plasmid containing the cargo...

... A., et al. "Rapid parallel measurements of macroautophagy and mitophagy in mammalian cells using a single...

...Western Ontario studying plant-based recombinant pharmaceuticals. Follow him on Twitter @AdamChinFatt     References...

...as well as the eFRET sensors, QuasAr-mOrange and MacQ-mCitrine. All of these sensors can detect action...

...secreted from producer cells also contain cellular macromolecules (e.g. proteins, nucleic acids) which possibly...

...gRNAs are released by endogenous tRNA processing machineries, specifically, RNaseZ and RNaseP. Although the...

...Application in Genetic Diseases: A Review.” Current pharmaceutical biotechnology. https://doi.org/10.2174/1389201021666200621161610...

...complicated (and again, expensive) the different machines are, and how many regulations are in place to ...

...large conference room puts butterflies in your stomach, the virtual approach might be less stressful. ...

...flow. Novel treatment options, as well as non-pharmacological solutions to modify the course of this condition...

... found in DNA. It then recruits transcription machinery to the site to induce gene expression. Thus, genes...

...about his clinical trial patients with advanced macular degeneration; Laurenz Studer discussed his work...

...provides greater spatiotemporal resolution than pharmacological or genetic manipulation of the signaling pathway...

...lysogenic. Lytic phages hijack the bacterial hosts machinery to make more viral particles. Eventually the cell...

...efficient gene deletion in B cells, T cells, macrophages, and dendritic cells, with no deleterious effects...

...samples. RNA is inherently less stable than most macromolecules used in scientific research such as DNA or ...

...through increasingly dense layers until the macromolecule density is equal to the buoyant force of the...

...non-interacting with) the cells’ own natural translation machinery; these are often incorporated into the cells via...

...some GPCRs further to respond to specific, pharmacologically-inert, small molecules. These new receptors...

...promoter. Experimental System Because transcription machinery differs between cell types or organisms, promoters...

...associations: common colds, COVID-19, norovirus (the stomach flu), and many more. Their infectious nature allows...

...with the community are particularly successful. Machine-learning denoising of raw data (CARE), segmentation...

...podcast segment As the primary cause for both the stomach flu and food-borne illnesses, noroviruses can infect...

..., repressing RecA and overexpressing the NHEJ machinery improved NHEJ accuracy in M. smegmatis (Yan et...

...expression AAVs have to infect cells, hijack host cell machinery, and synthesize a second strand of DNA before ...

...0005-2744(74)90240-x Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ (1979) Isolation of biologically...

...foreign dsRNA activates the innate immune response machinery of the host. This pathway has been clinically...

...10.1073/pnas.0700293104 Field J, Nikawa J, Broek D, MacDonald B, Rodgers L, Wilson IA, Lerner RA, Wigler M (...

...circumvent this problem, they co-injected CRISPR machinery with sperm into M phase oocytes, thus allowing...