We narrowed to 8 results for: Mac
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TypeGuide...rhodopsins Mac Light-activated outward proton pump from Leptosphaeria maculans 540 eMac 3.0 Mac with addition...Leptosphaeria maculans . Mac and its variants allow for inhibition of neurons using blue-green light. Mac variants...amplitude Examples: eArch3.0, eArchT3.0 Mac Leptosphaeria rhodopsin (Mac) is a blue-green light-activated proton...such as: Improved photocurrent amplitude Example: eMac3.0 Glossary of Microbial Opsin Variants Opsin Type...
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Chemogenetics Guide
TypeGuide...the antipsychotic clozapine and seems to be pharmacologically inert in mice and rats. However, CNO is back-metabolized...neurons through manipulation of ion channels arePharmacologically Selective Actuator Modules (PSAMs, pronounced...respond to specific small molecules termed Pharmacologically Selective Effector Molecules (PSEMs). PSAM...pre-requisite for mimicking clozapine's actions? Psychopharmacology, 178 (4), 451–460. https://doi.org/10.1007...cAMP Production in Striatopallidal Neurons. Neuropsychopharmacol, 38 (5), 854–862. https://doi.org/10.1038...arrestin-biased designer G protein-coupled receptor. Mol Pharmacol, 82 (4), 575–582. https://doi.org/10.1124/mol.112.080358... -
Molecular Biology Reference
TypeGuide...replication in bacteria by recruiting DNA replication machinery. The ori is critical for the ability of the plasmid...insert. The promoter recruits transcriptional machinery and can be specific to a certain species, tissue...only in bacteria by bacterial transcriptional machinery. For more information on antibiotic resistance... when sequencing is not 100% efficient and the machine cannot distinguish between the four labeled nucleotides... -
Adeno-associated virus (AAV) Guide
TypeGuide...replication as it activates the necessary cellular machinery to produce large amounts of rAAV vectors. The ... vector depends on the cell’s DNA replication machinery to synthesize the complementary strand, transgene... viral vectors for enhanced gene transfer . Pharmaceutical Research, 25 (3), 489–499. https://doi.org/...replication process where the virus uses the cell machinery to produce new viruses, eventually lysing the ... -
Antibody Guide
TypeGuide...can be detected either digitally by an imaging machine or by X-ray film. HRP cannot be used to distinguish...either X-ray film in a darkroom or an image capture machine. Special considerations The primary antibody must...direction based on the emission(s) read by the machine. Controls for cell sorting methods Flow cytometry...overlap to avoid confusing data. Check that your machine has appropriate lasers and filters for each fluorophore... -
Gamma-Retroviral Vector Guide
TypeGuide...Ravin, S. S., Su, L., Theobald, N., Choi, U., Macpherson, J. L., Poidinger, M., Symonds, G., Pond, S. ...Tejerizo, J. G., Abreu, S., Rubat, L., Nikoniuk, A., Macmorland, W., Horlock, C., Matsumoto, S., Williams, S.... -
Lentiviral Vector Guide
TypeGuide...immunotherapy and gene therapy. Biomedicine & Pharmacotherapy , 128 , 110276. https://doi.org/10.1016/j.biopha... -
CRISPR Guide
TypeGuide...Smith, S. B., Meadows, S. K., Roberts, B. S., Mackiewicz, M., Mendenhall, E. M., & Myers, R. M. (2015)...