We narrowed to 525 results for: ARL
-
TypeBlog PostPublishedNov. 28, 2017, 2 p.m....school’s equivalent of a senior thesis), I knew early on that I wanted to work with a partner. WPI’s emphasis...would launch our careers in science. Fast forward nearly 20 years and I am known by some colleagues as the...success are defined by ongoing mission fulfillment. Earlier this year, I joined Addgene’s Green Team, a like-minded...post-doc adviser almost never had lab meetings. In my nearly 4 years in the lab, we probably didn’t have more...
-
FLEx Technology and Optogenetics: Flipping the switch on gene expression with high spatial and temporal resolution
TypeBlog PostPublishedOct. 17, 2019, 12:28 p.m.... from Stanford University, led by neurobiologist Karl Deisseroth, combined optical and genetic methods...30503173. PubMed Central PMCID: PMC6317997. Deisseroth, Karl, et al. "Next-generation optical technologies for...17035522. Pubmed Central PMCID: PMC2820367. Deisseroth, Karl. "Optogenetics." Nature methods 8.1 (2011): 26. ...PMCID: PMC3979449. Fenno, Lief, Ofer Yizhar, and Karl Deisseroth. "The development and application of ... -
Cancer and the Immune System: Deciphering the Relationship
TypeBlog PostPublishedMarch 14, 2017, 2:30 p.m....contrast to the acute immune responses that eliminate early stage cancer cells, chronic inflammatory responses...types of immune cells. Dendritic cells (DCs) are particularly popular whole cell therapeutics because they...clinical trials, expansion of participants based on early results can enhance the positive effects of the ...cell deaths that help activate tumor responses. Similarly, some radiotherapies have caused increased death... -
Congratulations, Deck The Lab winners!
TypeBlog PostPublishedJan. 14, 2021, 1:30 p.m.... pic.twitter.com/drNBUdlQco — The Tarling-Vallim Lab (@TarlingVallim) December 19, 2020 In third place...post shared by Hannah Drury (@druryhannah) The Tarling-Vallim Lab’s first place-winning entry doubled ... -
Advice on Career Paths and the Green Card Process for International Researchers and Entrepreneurs
TypeBlog PostPublishedDec. 20, 2017, 2:33 p.m....scientific or scholarly research contributions in the field Evidence of authorship of scholarly books or articles...benefit from the applicant thinking about the process early, keeping good records, and planning for the route... articles (in scholarly journals with international circulation) in the field EB-1Bs historically have... -
A Scientist's Guide to Ebola
TypeBlog PostPublishedOct. 16, 2014, 3:01 p.m.... of Ebola representing the latest outbreak and earlier ones, along with links to the relevant scientific... and The New England Journal of Medicine have similarly curated their Ebola-related content. -And the ... in EBOV’s past, present, and future, don’t miss Carl Zimmer’s coverage on the subject in the New York... -
Inntags: Innovative Protein Epitope Tagging
TypeBlog PostPublishedNov. 10, 2015, 3:30 p.m.... that 20% of tagged proteins did not localize similarly to their untagged counterparts. These findings... for examining protein-protein interactions, particularly in single-molecule or high-throughput applications...methods (2015). PubMed PMID:26322837. 2. Stadler, Charlotte, et al. "Immunofluorescence and fluorescent-protein... -
Download Addgene’s Science Career Guide, Plus 8 Career Tips from Addgenies
TypeBlog PostPublishedFeb. 26, 2019, 1:40 p.m....organization/position exist yet?", you are in the early stages of creating an opportunity. That's how Addgene...Director of Science Product Management “I knew very early on that I wanted to be an artist/designer. But there...each one. Get the toughest steps out of the way early if you can.” - Eddy Page, Digital Media Production... -
Editor's Choice, August 2016
TypeBlog PostPublishedSept. 2, 2016, 1:32 p.m....number of out of office responses I’ve received). Clearly we have all of our writers to thank for the excellent...who wrote this month’s most popular blog post on early user experiences with CRISPR alternative, NgAgo....having trouble, to determine if there have been any early successes, and to find out what delivery techniques... -
Management for Scientists: Seeking Feedback
TypeBlog PostPublishedJan. 8, 2015, 2:34 p.m....reinventing the wheel is inefficient. An effective team regularly seeks expertise wherever it can be found. Listen...allies" – these are employees in your group that regularly step up to give feedback and fill you in on percolating...constructive input from your team: Solicit feedback regularly and often A one-time event doesn't work to get... -
Phage Directory: From Phage Therapy to a Repository of Phage Information
TypeBlog PostPublishedJan. 10, 2019, 2:38 p.m....the directory does not typically come out until nearly the last minute when all other options have been... phage alerts can be sent out to the directory earlier, but the researchers in the directory are volunteering...time and resources and there is a chance that an early request for phage may not be needed if other antibiotics... -
ReFigure: Save Scientific Figures into Dashboards and Share Your Insights
TypeBlog PostPublishedDec. 13, 2017, 3:20 p.m....resulting in “negative data” often dominate the early years of a project. Dissemination of the knowledge...selection of data found in full-length publications. As early career researchers, we wondered how we could make... guest blogger Girija Goyal! Girija Goyal is an early career researcher and cofounded ReFigure with Joe... -
History of CRISPR Cas - A tale of survival and evolution
TypeBlog PostPublishedNov. 25, 2013, 10:12 p.m....biological blockbuster known as the CRISPR (clustered regularly interspaced palindromic repeats) Cas (CRISPR associated...have been identified that neutralize CRISPR/Cas. Earlier this year, expression of 1 of 5 anti-CRISPR genes... Mali P, Yang L, Esvelt KM, Aach J, Guell M, DiCarlo JE, Norville JE, Church GM. Science. 2013 Jan; ... -
Science Careers: Unruly Interests Feed Many Paths
TypeBlog PostPublishedSept. 26, 2017, 12:12 p.m.... a look at the blog ‘Scholarly Kitchen’ for a glimpse into the world of scholarly publishing. And see ...developing a career Developmental biology caught me early on: a simple egg is packed with information. I am... -
Plasmids 101: A Brief History of Plasmids and an Improved eBook!
TypeBlog PostPublishedOct. 29, 2015, 2:30 p.m....began to study other extrachromosomal particles, particularly Resistance or R-factors. Like F-factors, R-factors...napkins to notebooks Although discovered in the early 1950s, it took until the 1970s for plasmids to gain...Stanley Falkow, Stanley Cohen, Herbert Boyer, and Charles Brinton concocted a wild idea of using the newly... -
Don’t Wait To Launch Your Health Science Startup
TypeBlog PostPublishedAug. 25, 2015, 2:30 p.m....miLab, a Boston-based startup focused on empowering early-stage scientists. You can think of miLab as a sort... next generation companies. We launched in the early spring of 2015 and since that time have received...capital for such a fund is an impossibility at our early stage. After each pitch we made, we considered ... -
The Crispr Babies Saga Shows the Need for Action, Not More Delays
TypeBlog PostPublishedDec. 20, 2018, 1:15 p.m.... cats, Harley and Lexi, and a clutter ofoutdoors-only spiders, all of whom are named Charlotte, all of...technique was feasible, three separate things happened nearly simultaneously: The Wellcome Trust funded a center... -
Addgene Depositors Get More Citations
TypeBlog PostPublishedApril 20, 2017, 2:30 p.m....original 2013 gene editing paper on CRISPR/Cas amassed nearly 2,400 citations in its first four years (1). In... over 6,500 requests for these plasmids. While clearly an outlier, this story had us wondering: is there...at the MIT Sloan School of Management. She is particularly interested in exploring how innovative tools... -
With Our New Viral Service, We're Taking CRISPR Further!
TypeBlog PostPublishedDec. 6, 2016, 3:30 p.m....that, for many groups, may not be worthwhile. Particularly if in the end all they want to do is to quickly...size of the SpCas9 nuclease (~4.2 kb) this is a particularly prominent problem in CRISPR genome editing experiments...ready-to-use lentiviral preps. Each library uses nearly 80,000 gRNAs to target around 20,000 individual... -
Management for Scientists: Delegating is Key
TypeBlog PostPublishedFeb. 20, 2015, 8:30 p.m....assignee and this is a recipe for bad outcomes. Clearly articulate the desired outcomes. Begin with the... the heart of delegating for success. Meet regularly before during and after the assignment to discuss...calendar even if it is just 15 minutes a week. Clearly identify constraints and boundaries. Where are ...