We narrowed to 139 results for: tox

...perform retrograde tracing, but often at the cost of toxicity, low expression, or poor scalability.  Scientists...

...plasmid. Viral transduction is also generally less toxic to cells than transfections, preserving cell viability...

...Leakiness If you’re expressing a gene that may be toxic, it’s important that your inducible promoter not...

...As nucleases may have off-target effects and/or toxicity, it would be advantageous to instead use a preexisting...

...results to rapamycin inhibition. To assess TRIM21 toxicity, Clift et al. created stable cell lines overexpressing...

...desired product while avoiding the accumulation of toxic intermediates or the shuttling of the intermediates...

...labeling approach, is an alternative option but it’s toxic to tissues and model organisms. Detecting RNA-protein...

...Slaymaker et al. showed that these mutants are not toxic to HEK cells and that similar mutations can improve...

... using the rTetR system, but Cre-DOG lacks the toxicity that can be seen with high levels of transcription...

...stop it from being used. One thing is that Cas9 is toxic. When cells carry CRISPR circuitry, it can slow ...

...added fresh to solutions. It is also volatile and toxic (and smells bad!), so be sure to use it under a ...

... the plasmid will produce anything dangerous or toxic to humans in bacteria, select “yes” in the drop-...

... long-term transgene expression and negligible toxicity. However, their production is more complex and...

...First, these high levels of viral replication are toxic. Second, infecting subsequently higher and higher...

... efficiency in cells that are sensitive to the toxicity of polybrene (e.g., hematopoietic or primary cells...

...genome, removing the risk of oncogenicity or genotoxicity seen with other vectors (Lukashev et al., 2016...

...key attribute for neuronal tracing. Labeling was nontoxic and activity-dependent, with more labeling across...

...aggregation-prone tetrameric fluorescent proteins can be. Cytotoxicity, improper localization, and decreased functionality...

... for a single insert), mostly due to the use of toxic ccdB to prevent any non-recombinant vectors from...

...acid (a by-product of cellular metabolism that is toxic to the cells), and need to be split very soon. There...