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Showing: 161 - 180 of 516 results
  1. Donations from Addgene to Yield Answers for Rare Disease Researchers

    Type
    Blog Post
    Published
    Sept. 15, 2015, 2:30 p.m.
    ...by mutations in the OCRL1 gene that leads to the early death of young patients as their kidneys fail. The...interested in XP out of a desire to understand the early events in the transformation of healthy cells into...
  2. Creating accessible biology activities in schools with BioBits

    Type
    Blog Post
    Published
    Aug. 2, 2018, 12:56 p.m.
    ...thinking: I wish I had this kind of experience earlier! After all, students build circuits in physics... about operating the rest of the car as well. Similarly, cell free expression systems contain all the ...
  3. Celebrate National Book Month with Addgene

    Type
    Blog Post
    Published
    Oct. 3, 2019, 12:47 p.m.
    ...insects, mammals, and plants, among others. I particularly enjoyed the emphasis that microbes are neither...last 8 years. Since then, we’ve read books across nearly every genre you can imagine: gothic, mystery, sci-fi...
  4. Plasmids 101: Gram Negative and Positive Bacteria

    Type
    Blog Post
    Published
    Aug. 2, 2022, 1:15 p.m.
    ...decolorized as gram negative. A German scientist, Carl Weigert, later expanded on Gram’s discovery, adding...resources.   Bruckner, M. Gram Staining. https://serc.carleton.edu/microbelife/research_methods/microscopy/gramstain.html...
  5. Using CRISPR/Cas9 to Edit Disease Out of the Genome

    Type
    Blog Post
    Published
    June 23, 2022, 1:15 p.m.
    ...They are targeting the genes responsible for both early onset and late onset AD. In this study, the group...autosomal-dominant mutations that have been connected to the early onset of Alzheimer’s disease, as well as those that...
  6. The MTA at Addgene

    Type
    Blog Post
    Published
    July 23, 2024, 2:17 p.m.
    ...MTAs by the Provider and Recipient (in Addgene parlance, the depositor and requestor) organizations. Over...depends on things being organized, tracked, and clearly communicated. And that’s where MTAs, and similar...
  7. Viral Vectors 101: Inverted Terminal Repeats

    Type
    Blog Post
    Published
    Oct. 19, 2023, 1:15 p.m.
    ...because they demonstrate high promoter activity (Earley et al. 2020), but non-AAV2 ITRs can be used to ...Addgene's AVV guide AAV Viral Preps References  Earley, L. F., Conatser, L. M., Lue, V. M., Dobbins, A...
  8. Addgene Welcomes John Doench to the Advisory Board

    Type
    Blog Post
    Published
    Aug. 13, 2015, 2:30 p.m.
    ...specificity in the miRNA regulatory process. This early research is still relevant to his work at the Broad...screens to learn more about cancer biology in Ed Harlow’s group at Harvard Medical School and then applied...
  9. Plasmids 101: Inducible Promoters

    Type
    Blog Post
    Published
    Jan. 18, 2018, 2:34 p.m.
    ...between cell types or organisms, promoters are similarly variable. Bacterial promoters only work in prokaryotic...related species from which they were derived. Similarly, the various eukaryotic cell types (mammalian,...
  10. Behind the scenes: Addgene’s new search engine and more

    Type
    Blog Post
    Published
    Dec. 12, 2019, 2:22 p.m.
    ...results. The footer and improved menus we launched earlier in the year, as well as our redesigned homepage...categorization of our information in order to more granularly customize the search engine, and a scoping mechanism...
  11. Antibodies 101: Isotypes

    Type
    Blog Post
    Published
    Oct. 19, 2021, 1:15 p.m.
    ... in Health and Disease. 5th edition. New York: Garland Science; 2001. Structural variation in immunoglobulin... in Health and Disease. 5th edition. New York: Garland Science; 2001. The distribution and functions of...
  12. How to Keep a Lab Notebook for Bioinformatic Analyses

    Type
    Blog Post
    Published
    June 2, 2016, 2:30 p.m.
    ...inspired you to perform this analysis. Having a clearly stated, specific goal for each analysis will help...student at University of Pennsylvania. She is particularly interested in science communication and epigenetics...
  13. Form Your Own Peer Mentoring Group: A How-To Guide for Scientists

    Type
    Blog Post
    Published
    Feb. 18, 2014, 4:22 p.m.
    ...ends, some 50% of these groups continue to meet regularly, providing ongoing support, advice and accountability...most hits. Commit to a meeting schedule and meet regularly no matter what, even if one person can’t make ...
  14. Choosing the B(right)est Fluorescent Protein: Photostability

    Type
    Blog Post
    Published
    June 8, 2017, 2:30 p.m.
    ...absorb the excitation light less efficiently. Similarly, decreasing the power of the excitation light ...experiments. As the photobleaching rate is not linearly related to power, the conclusions reached at high...
Showing: 161 - 180 of 516 results