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Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

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We narrowed to 19 results for: HR2

Showing: 1 - 19 of 19 results

  1. New Viral Vectors - Winter 2025

    Type
    Blog Post
    Published
    Jan. 28, 2025, noon
    ... viral prep AiP13755: pAAV-AiE0743m_3xC2-minBG-ChR2(H134R)-EYFP-WPRE3-BGHpA (Alias: CN3755) AAV-PHPeB...Control Gordon Fishell New viral prep pAAV_BiSSTe10_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell...Control Gordon Fishell New viral prep pAAV_BiCHATe27_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell...Control Gordon Fishell New viral prep pAAV_BiVIPe4_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell ...Control Gordon Fishell New viral prep pAAV_BiLAMP5e3_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell...Control Gordon Fishell New viral prep pAAV_BiPVe4_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell ...Control Gordon Fishell New viral prep pAAV_BiPVe3_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell ...

  2. Channelrhodopsins with improved light sensitivity for minimally-invasive optogenetics

    Type
    Blog Post
    Published
    Nov. 3, 2020, 2:15 p.m.
    ...intensity than existing channelrhodopsins CoChR and/or ChR2(H134R). Designer channelrhodopsins paired with ...injections. When packaged in PHP.eB, ChRgers and ChR2(H134R) both reach the brain, but individual neurons...multiplicity of infection (MOI) makes it challenging for ChR2(H134R) to function because it’s lower conducence... a burst of light that could activate ChRger2 or ChR2(H134R) when they poked their nose into a hole in...what was seen with ChRger2 expressing mice, while ChR2(H134R) expressing mice did not have this self-stimulation...systemic delivery with PHP.eB compared to the existing ChR2(H134R).  In the second experiment, ChRger2 was delivered...the right M2 are activated, but mice that received ChR2(H134R) did not turn. Left-turning behavior in ChRger2...

  3. New and Upcoming Viral Vectors - December 2019

    Type
    Blog Post
    Published
    Dec. 19, 2019, 2:40 p.m.
    ...Fon hChR2(H134R)-EYFP 26975 AAVrg pAAV-CaMKIIa-hChR2(H134R)-mCherry 26976 AAV5 pAAV-hSyn-hChR2(H134R...packaged hChR2(H134R) plasmids from Karl Deisseroth’s lab, which includes pAAV-hSyn Con/Fon hChR2(H134R)...H134R)-mCherry 26973 AAVrg pAAV-hSyn-hChR2(H134R)-EYFP   Control AAV Control AAV allow researchers...

  4. New and Upcoming Viral Vectors - May 2020

    Type
    Blog Post
    Published
    May 28, 2020, 1:15 p.m.
    ...AAV1 pAAV-CAG-FLEXFRT-ChR2(H134R)-mCherry Connie Cepko 83898 AAVrg pAAV-mDlx-ChR2-mCherry-Fishell-3 Gordon...Lentiviral preps for expressing SARS-CoV-2 proteins ChR2 for targeted expression DREADDs GFP dependent Cre...have expanded our AAV collection to include two new ChR2 constructs that allow for targeted expression. Plasmid...available in AAV1 for Flp-dependent expression of ChR2(H134R) bound to an mCherry reporter. We now also...AAVrg for plasmid 83898, which targets expression of ChR2 to forebrain GAB-ergic interneurons through the ...

  5. New and Upcoming Viral Vectors - September 2019

    Type
    Blog Post
    Published
    Sept. 12, 2019, 1 p.m.
    ... them! Controls pAAV-hSyn-hChR2(H134R)-EYFP (26973-AAVrg) pAAV-hSyn-hChR2(H134R)-mCherry (26976-AAV5)...(104496-AAVrg) Optogenetics pAAV-hSyn Con/Fon hChR2(H134R)-EYFP (55645-AAV5)  Additional resources...

  6. The Materials Science of Optogenetics Experiments

    Type
    Blog Post
    Published
    Sept. 17, 2015, 2:30 p.m.
    ...      In the video above, Channelrhodopsin 2 (Chr2) has been expressed in the motor cortex of a mouse... light-gated cation channel, Channelrhodopsin 2 (ChR2), exists in several states: closed/light receptive.... If you deliver a continuous stream of photons, Chr2 will open but will not be given an opportunity to...

  8. Deciphering the Mysteries of Behavior with Viral Vectors

    Type
    Blog Post
    Published
    Sept. 17, 2019, 12:40 p.m.
    ...these neurons via the channel Channelrhodopsin 2 (ChR2) reduced glutamate transmission from the mPFC projections...Cre-dependent expression of  Channelrhodopsin 2 (ChR2), a modified receptor protein that activates neurons...

  9. Important Considerations in Optogenetics Behavioral Experiments

    Type
    Blog Post
    Published
    Oct. 1, 2015, 2:30 p.m.
    ...the early response gene c-fos. For example, using Chr2 stimulation should result in robust increases in...region after stimulation compared to controls without Chr2. c-Fos is a reliable and widely used molecular marker...

  10. Viral Vectors 101: Optogenetic Tools

    Type
    Blog Post
    Published
    June 27, 2023, 1:15 p.m.
    ...controlling neuronal activity, channelrhodopsin-2 (ChR2), a blue light-activated cation channel, from the...opsin.      Figure 2: Diagram of excitatory (ChR2) activation by light showing ions flowing with the...

  11. New Viral Vectors - Spring 2025

    Type
    Blog Post
    Published
    April 29, 2025, 1:30 p.m.
    ...Optogenetics Ofer Yizhar New viral tool pAAV-Ef1a-fDIO hChR2(H134R)-EYFP AAVrg Optogenetics Karl Deisseroth New...

  13. New Viral Vectors - Fall 2024

    Type
    Blog Post
    Published
    Oct. 3, 2024, 1:15 p.m.
    ...Optogenetics Karl Deisseroth New serotype pAAV-hSyn-hChR2(H134R)-EYFP AAV2 Optogenetics Karl Deisseroth New...

  17. Hot Plasmids - August 2020

    Type
    Blog Post
    Published
    Aug. 18, 2020, 1:15 p.m.
    ...hDlx-Flex-dTomato, mDlx-GCaMP6f, hDlx-GiDREADD-dTomato and mDlx-ChR2-mCherry. Find these AAVs at Addgene ...
Showing: 1 - 19 of 19 results