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Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

In Category

We narrowed to 29 results for: HR2

Showing: 1 - 20 of 29 results

  1. New Viral Vectors - Winter 2025

    Type
    Blog Post
    ... viral prep AiP13755: pAAV-AiE0743m_3xC2-minBG-ChR2(H134R)-EYFP-WPRE3-BGHpA (Alias: CN3755) AAV-PHPeB...Control Gordon Fishell New viral prep pAAV_BiSSTe10_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell...Control Gordon Fishell New viral prep pAAV_BiCHATe27_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell...Control Gordon Fishell New viral prep pAAV_BiVIPe4_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell ...Control Gordon Fishell New viral prep pAAV_BiLAMP5e3_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell...Control Gordon Fishell New viral prep pAAV_BiPVe4_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell ...Control Gordon Fishell New viral prep pAAV_BiPVe3_ChR2_mCherry AAV-PHPeB Optogenetics Gordon Fishell ...

  2. Channelrhodopsins with improved light sensitivity for minimally-invasive optogenetics

    Type
    Blog Post
    ...intensity than existing channelrhodopsins CoChR and/or ChR2(H134R). Designer channelrhodopsins paired with ...injections. When packaged in PHP.eB, ChRgers and ChR2(H134R) both reach the brain, but individual neurons...multiplicity of infection (MOI) makes it challenging for ChR2(H134R) to function because it’s lower conducence... a burst of light that could activate ChRger2 or ChR2(H134R) when they poked their nose into a hole in...what was seen with ChRger2 expressing mice, while ChR2(H134R) expressing mice did not have this self-stimulation...systemic delivery with PHP.eB compared to the existing ChR2(H134R).  In the second experiment, ChRger2 was delivered...the right M2 are activated, but mice that received ChR2(H134R) did not turn. Left-turning behavior in ChRger2...

  3. New and Upcoming Viral Vectors - December 2019

    Type
    Blog Post
    ...Fon hChR2(H134R)-EYFP 26975 AAVrg pAAV-CaMKIIa-hChR2(H134R)-mCherry 26976 AAV5 pAAV-hSyn-hChR2(H134R...packaged hChR2(H134R) plasmids from Karl Deisseroth’s lab, which includes pAAV-hSyn Con/Fon hChR2(H134R)...H134R)-mCherry 26973 AAVrg pAAV-hSyn-hChR2(H134R)-EYFP   Control AAV Control AAV allow researchers...

  4. New and Upcoming Viral Vectors - May 2020

    Type
    Blog Post
    ...AAV1 pAAV-CAG-FLEXFRT-ChR2(H134R)-mCherry Connie Cepko 83898 AAVrg pAAV-mDlx-ChR2-mCherry-Fishell-3 Gordon...Lentiviral preps for expressing SARS-CoV-2 proteins ChR2 for targeted expression DREADDs GFP dependent Cre...have expanded our AAV collection to include two new ChR2 constructs that allow for targeted expression. Plasmid...available in AAV1 for Flp-dependent expression of ChR2(H134R) bound to an mCherry reporter. We now also...AAVrg for plasmid 83898, which targets expression of ChR2 to forebrain GAB-ergic interneurons through the ...

  5. New and Upcoming Viral Vectors - September 2019

    Type
    Blog Post
    ... them! Controls pAAV-hSyn-hChR2(H134R)-EYFP (26973-AAVrg) pAAV-hSyn-hChR2(H134R)-mCherry (26976-AAV5)...(104496-AAVrg) Optogenetics pAAV-hSyn Con/Fon hChR2(H134R)-EYFP (55645-AAV5)  Additional resources...

  6. The Materials Science of Optogenetics Experiments

    Type
    Blog Post
    ...      In the video above, Channelrhodopsin 2 (Chr2) has been expressed in the motor cortex of a mouse... light-gated cation channel, Channelrhodopsin 2 (ChR2), exists in several states: closed/light receptive.... If you deliver a continuous stream of photons, Chr2 will open but will not be given an opportunity to...

  8. Deciphering the Mysteries of Behavior with Viral Vectors

    Type
    Blog Post
    ...these neurons via the channel Channelrhodopsin 2 (ChR2) reduced glutamate transmission from the mPFC projections...Cre-dependent expression of  Channelrhodopsin 2 (ChR2), a modified receptor protein that activates neurons...

  10. Viral Vectors 101: Optogenetic Tools

    Type
    Blog Post
    ...controlling neuronal activity, channelrhodopsin-2 (ChR2), a blue light-activated cation channel, from the...opsin.      Figure 2: Diagram of excitatory (ChR2) activation by light showing ions flowing with the...

  11. New Viral Vectors - Spring 2025

    Type
    Blog Post
    ...Optogenetics Ofer Yizhar New viral tool pAAV-Ef1a-fDIO hChR2(H134R)-EYFP AAVrg Optogenetics Karl Deisseroth New...

  12. New Viral Vectors - Fall 2024

    Type
    Blog Post
    ...Optogenetics Karl Deisseroth New serotype pAAV-hSyn-hChR2(H134R)-EYFP AAV2 Optogenetics Karl Deisseroth New...

  17. Hot Plasmids - August 2020

    Type
    Blog Post
    ...hDlx-Flex-dTomato, mDlx-GCaMP6f, hDlx-GiDREADD-dTomato and mDlx-ChR2-mCherry. Find these AAVs at Addgene ...

  18. Optogenetics AAV Preps

    Type
    Collection
    ...collection. Opsin Excitatory Wild-type ChR2 ChR2/H134R soCoChR ChR2/other mutants Chronos, Chrimson, ChRmine...20071 pACAGW-ChR2-Venus-AAV CAG ChR2 Venus Constitutive 1, 9 Svoboda 83898 pAAV-mDlx-ChR2-mCherry-Fishell...mCherry-Fishell-3 Dlx ChR2 mCherry Constitutive 1, 9, rg* Fishell 135634 pAAV-S5E2-ChR2-mCherry nEF ChR2 mCherry Constitutive...Foff 2.0-ChR2-mCherry nEF ChR2 mCherry Cre dependent 8 Deisseroth 137144 pAAV-nEF-Coff/Fon-ChR2-mCherry...mCherry nEF ChR2 mCherry Flp dependent 8 Deisseroth 137163 pAAV-nEF-Con/Foff 2.0-ChR2-EYFP nEF ChR2 EYFP Cre...pAAV-CAG-FLEXFRT-ChR2(H134R)-mCherry CAG ChR2/H134R mCherry Flp dependent 1 Cepko 55639 pAAV-Ef1a-fDIO hChR2(H134R...Syn ChR2/H134R GFP Constitutive 8, rg* Boyden 100054 pAAV.CAG.hChR2(H134R)-mCherry.WPRE.SV40 CAG ChR2/H134R...

  19. Penn Vector Core Partnership with Addgene

    Type
    Collection
    ...AAV-FLEX-rev-ChR2-tdtomato Optogenetics Scott Sternson AV-1-20071P 20071-AAV1 pACAGW-ChR2-Venus-AAV Optogenetics...pAAV-hSyn-hChR2(H134R)-EYFP Optogenetics Karl Deisseroth AV-1-26975 26975-AAV1 pAAV-CaMKIIa-hChR2(H134R)-...pAAV-hSyn-hChR2(H134R)-EYFP Optogenetics Karl Deisseroth AV-5-26975 26975-AAV5 pAAV-CaMKIIa-hChR2(H134R)-...pACAGW-ChR2-Venus-AAV Optogenetics Karel Svoboda AV-9-20297P 20297-AAV9 pAAV-EF1a-double floxed-hChR2(H134R...pAAV-hSyn-hChR2(H134R)-EYFP Optogenetics Karl Deisseroth AV-9-26975 26975-AAV9 pAAV-CaMKIIa-hChR2(H134R)-...pAAV-CaMKIIa-hChR2(E123A)-EYFP Optogenetics Karl Deisseroth AV-9-35506 35506-AAV9 pAAV-CaMKIIa-hChR2(E123A)-...pAAV-Ef1a-DIO hChR2(E123A)-EYFP Optogenetics Karl Deisseroth AV-9-35509 35509-AAV9 pAAV-Ef1a-DIO hChR2(E123T/...

  20. Caltech Systemic Capsids

    Type
    Collection
    ...pAAV-hSyn-hChR2(H134R)-EYFP Syn Activator ChR2 Deisseroth 20298 pAAV-EF1a-double floxed-hChR2(H134R)-EYFP-WPRE-HGHpA...Cre-dependent ChR2 Deisseroth 127090 pAAV-CAG-DIO-ChR2(H134R)-eYFP CAG Activator, Cre-dependent ChR2 Gradinaru...213815 pAAV_BiSSTe10_ChR2_mCherry BiSSTe10 Activator ChR2 Fishell 213830 pAAV_BiCHATe27_ChR2_mCherry BiCHATe27...BiCHATe27 Activator ChR2 Fishell 213856 pAAV_BiVIPe4_ChR2_mCherry BiVIPe4 Activator ChR2 Fishell 213915 pAAV_BiLAMP5e3... pAAV_BiLAMP5e3_ChR2_mCherry BiLAMP5e3 Activator ChR2 Fishell 213937 pAAV_BiPVe4_ChR2_mCherry BiPVe4 Activator... Activator ChR2 Fishell 213941 pAAV_BiPVe3_ChR2_mCherry BiPVe3 Activator ChR2 Fishell 213945 pAAV_BiSSTe4...Dimidschstein 135634 pAAV-S5E2-ChR2-mCherry E2 regulatory element Activator ChR2 Dimidschstein 214846 AiP13755...
Showing: 1 - 20 of 29 results