...Shmakov S, Makarova KS, Semenova E, Minakhin L, Severinov K, Regev A, Lander ES, Koonin EV, Zhang F (2016...Slaymaker IM, Makarova KS, Essletzbichler P, Volz SE, Joung J, van der Oost J, Regev A, Koonin EV, Zhang F (2015...detect nucleic acids at the atomolar level. The Zhang lab has adapted natural RNase activity of the Cas13...Cas13 (C2c2) was first identified in 2016 by the Zhang lab as an RNA guided RNase (Abudayyeh et al 2016...specific reporter and the activation of Csm6. The Zhang lab showed that, by adding Csm6 and a Csm6 specific...Applications of the SHERLOCK detection system The Zhang lab demonstrated that SHERLOCK could reliably distinguish... in the field (Myhrvold et al., 2018). Now, the Zhang lab has shared a protocol for using SHERLOCK to ...