...MEK1 phosphomimetic residues in the above study with phosphoserine (to create a pSer/phosphomimetic dual... most common of which is the utilization of phosphomimetic residues. The phosphorylated residue of interest...but can be made constitutively active through phosphomimetic mutation of these residues. Due to the limitations...limitations previously mentioned, phosphomimetic mutations on the activation loop do not fully activate ...elevated kinase activity over 70-fold over dual phosphomimetic mutation. This emphasizes the advantages of...into recombinant proteins as an alternative to phosphomimetic mutation. Creating phosphoserine-incorporated...

..., starvation or the use of caloric restriction mimetics trigger autophagy and, in a mouse model led to...Pietrocola, Federico, et al. "Caloric restriction mimetics enhance anticancer immunosurveillance." Cancer...

...head-to-head comparative study under conditions that best mimic the intended application. The three key properties...their practical brightness in a system closely mimicking the future application. In figure 2 we provide...

...scientists think that chromoproteins could be used for mimicry and camouflage. An anemone’s red colored tentacles...1: The sea anemone's red color can be used for mimicry. Image: Bernard Spragg. Advantages of using ...

...S., et al. "Broccoli: rapid selection of an RNA mimic of green fluorescent protein by fluorescence-based...Structural basis for activity of highly efficient RNA mimics of green fluorescent protein." Nature structural...

... ligand from the Bryan Roth lab and Takafumi Minamimoto’s lab known as deschloroclozapine (DCZ) has been...

...Waldron Organoids are three-dimensional cultures that mimic aspects of organ morphology and physiology in vitro...

...implementation of expression systems to accurately mimic a disease phenotype. CRISPR can also be used to...

...demonstrating the use of CRISPR-based RNA scaffolds to mimic natural transcriptional programs on multiple genes...

...co-working, the idea is not necessarily to chat, but to mimic your usual work environment.  Be kind to yourself...

... both genetic and expression control systems to mimic illness on a molecular level. Atlas resource The...

...animal models. In these cases, they are designed to mimic the human lymphatic system or even the human skin...

...protein site-specifically to alter its function, mimic a biologically relevant modification, or add in ...

... a well-controlled environment, but they do not mimic the natural situation. Measuring photostability ...

...proteins, around 14-15 kDs in size. These are antibody mimics and are not closely related to antibodies. Instead...

...the Biodesign Center for Molecular Design and Biomimetics and the School of Molecular Sciences at Arizona...

...heterozygosity in the population, meaning they more closely mimic the genetic diversity of the human population. Outbred...

... JA (2017) Disabling Cas9 by an anti-CRISPR DNA mimic. Sci Adv 3:e1701620 . https://doi.org/10.1126/sciadv...

...ligand co-developed by Bryan Roth's and Takafumi Minamimoto's lab called deschloroclozapine (DCZ) shows promise...

..., Kiefl, E., Moody, T., Rice, P. A., Yu, M. K., Mimee, M., Chang, E. B., Ruscheweyh, H.-J., Sunagawa, ...