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  1. Rett Syndrome

    Type
    Collection
    ...MECP2 mutation database (Link opens in a new window) OMIM Rett Syndrome - Rett syndrome curated literature...literature information (Link opens in a new window) OMIM MECP2 - MECP2 curated literature information (Link opens...
  2. Using Phosphoserine to Study Protein Phosphorylation

    Type
    Blog Post
    ...MEK1 phosphomimetic residues in the above study with phosphoserine (to create a pSer/phosphomimetic dual... most common of which is the utilization of phosphomimetic residues. The phosphorylated residue of interest...but can be made constitutively active through phosphomimetic mutation of these residues. Due to the limitations...limitations previously mentioned, phosphomimetic mutations on the activation loop do not fully activate ...elevated kinase activity over 70-fold over dual phosphomimetic mutation. This emphasizes the advantages of...into recombinant proteins as an alternative to phosphomimetic mutation. Creating phosphoserine-incorporated...
  3. Antibody Guide

    Type
    Collection
    ...from ankyrin repeat proteins. These are antibody mimics instead of modified antibodies and are not closely...
  4. The Fluorescent Vegetables in Aptamer Soup

    Type
    Blog Post
    ...S., et al. "Broccoli: rapid selection of an RNA mimic of green fluorescent protein by fluorescence-based...Structural basis for activity of highly efficient RNA mimics of green fluorescent protein." Nature structural...
  5. Antibodies 101: Affinity Reagents

    Type
    Blog Post
    ...proteins, around 14-15 kDs in size. These are antibody mimics and are not closely related to antibodies. Instead...
  6. Viral Vectors 101: Chemogenetics

    Type
    Blog Post
    ...ligand co-developed by Bryan Roth's and Takafumi Minamimoto's lab called deschloroclozapine (DCZ) shows promise...
Showing: 1 - 20 of 36 results