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Showing: 1 - 3 of 3 results
  1. Antibodies 101: Flow Compensation

    Type
    Blog Post
    Published
    May 16, 2024, 1:15 p.m.
    ...applied to APC-Cy7 against APC to correct for this bleed. A compensation value of 3.7 for APC into APC-Cy7 applied...you will need compensation between APC and APC-Cy7; PE and PE-Cy7; APC-Cy7 and PE-Cy7; or BV421 and BV51...voltages.  Figure 1A shows a single-color APC control, with APC and APC-CY7 plotted against each other. Since... out of APC-Cy7. After increasing the compensation values for APC against APC-Cy7, the populations are...only be positive for APC, yet it seems as if the beads are also positive for APC-Cy7. You therefore would...would say that APC is “bleeding,” or spilling over, into APC-Cy7 channel and needs to be compensated out... showing an APC single-color control sample before (A) and after (B) compensation with APC-Cy7. The positive...
  2. Cancer and the Immune System: Deciphering the Relationship

    Type
    Blog Post
    Published
    March 14, 2017, 2:30 p.m.
    ...: Suppressing Function Antigen presenting cells (APCs) that would normally alert the rest of the immune...growth factor beta (TGFβ) and IL-10 that suppress APCs. T cells that would normally attack the cancer cells... turns off T cell function upon interaction with APCs. Furthermore, tumor cells alter their cell-surface...proximity to the tumor; chemokine-aided activation of APCs produces modified dendritic cells (DCs) and macrophages...
Showing: 1 - 3 of 3 results