Cancer and the Immune System: Deciphering the Relationship
Type
Blog Post
...:
Suppressing Function
Antigen presenting cells (APCs) that would normally alert the rest of the immune...growth factor beta (TGFβ) and IL-10 that suppress APCs. T cells that would normally attack the cancer cells... turns off T cell function upon interaction with APCs. Furthermore, tumor cells alter their cell-surface...proximity to the tumor; chemokine-aided activation of APCs produces modified dendritic cells (DCs) and macrophages...