...Deletion and replacement of long genomic sequences The PEDAR strategy engineered by Wen Xue’s lab also uses paired...with or without small insertions. But, instead, PEDAR couples this deletion process to a prime editing...are templated by the 3′ extension of the pegRNAs. PEDAR is capable of correcting larger genomic rearrangements...Read the paper in Nature Biotechnology Find the PEDAR plasmids   Additional resources on the Addgene...

...the eighth day of CRISPR, Addgene gave to me: the PEDAR strategy to delete and replace long genomic sequences...

... post was contributed by guest blogger Joachim Goedart, an assistant professor at the Section of Molecular...

... post was contributed by guest blogger Joachim Goedart, an assistant professor at the Section of Molecular...

... through Addgene The Vaithi Arumugaswami lab at Cedars-Sinai Medical Center has kindly constructed and...