3 Tips to Improve HDR Efficiency for CRISPR Editing in Human Cells
Type
Blog Post
Published
Sept. 5, 2017, 1:58 p.m.
...genes associated with dementia, such as APP and PSEN1, in most cases the intended HDR events were corrupted...probably due to concomitant NHEJ repair. At the PSEN1 locus, over 90% of the HDR edited alleles had unwanted...