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Enter a sequence to perform a BLAST-based search of Addgene plasmid sequence databases.

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We narrowed to 2 results for: mlh1

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  1. What's New in CRISPR - November 2021

    Type
    Blog Post
    Published
    Nov. 18, 2021, 2:15 p.m.
    ...dominant negative mutation in MLH1 (PE4 = PE2+MLH1dn and PE5 = PE3+MLH1dn). Silent mutations added near...

  2. Prime Editing: Adding Precision and Flexibility to CRISPR Editing

    Type
    Blog Post
    Published
    Jan. 13, 2025, 9:49 p.m.
    ...engineered a dominant-negative mutant of the protein MLH1, a component of the MutSα–MutLα mismatch repair ...Transiently co-express mismatch repair inhibitor MLH1dn Promote desired resolution of heteroduplex ...
Showing: 1 - 2 of 2 results