CRISPR Plasmids - Prime Edit
Type
Collection
...PE4 — PE2 plus MLH1 (a protein component of MMR) mutant to inhibit MMR PE5 — PE3 plus MLH1 mutant to inhibit...
We narrowed to 3 results for: mlh1
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What's New in CRISPR - November 2021
TypeBlog Post...dominant negative mutation in MLH1 (PE4 = PE2+MLH1dn and PE5 = PE3+MLH1dn). Silent mutations added near... -
Prime Editing: Adding Precision and Flexibility to CRISPR Editing
TypeBlog Post...engineered a dominant-negative mutant of the protein MLH1, a component of the MutSα–MutLα mismatch repair ...Transiently co-express mismatch repair inhibitor MLH1dn Promote desired resolution of heteroduplex ...