We narrowed to 6 results for: p53

...L-MYC and LIN28 pCXLE-hOCT3/4-shp53-F 27077 OCT3/4 and shRNA against p53 pCXWB-EBNA1 37624 transient...efficiency through the expression of a shRNA against p53, a modified reprogramming factor cocktail, and viral...completely understood, the addition of an shRNA for P53 and replacing C-MYC with L-MYC in the episomal reprogramming... induced pluripotent stem cell generation by the p53-p21 pathway. Nature, 2009. 460(7259): p. 1132-5. ...It has been shown previously that suppression of TP53 enhances iPSC generation as does replacing C-MYC...

...and structurally complex. The tumor suppressor TP53 (p53) is one example of these difficult-to-study genes... GC. HiBiT-TP53 expression was detected by blotting with LgBiT, and the authors used a p53 response-element...Next, the authors explored how these variants of p53 shape chemosensitivity and mechanistic drug responses...endogenous wild-type protein. Together, the work links p53 mutations to treatment outcomes and provides a HiBiT-enabled...explore TP53 biology. They first identified that in a set of patients with gastric cancer (GC), TP53 was ...(Kamio et al., 2025). They designed HiBiT-tagged TP53 constructs, one with an R175H mutation to match ...expression with a minimally disruptive tag. Find HiBiT-TP53 Fusion Vector at Addgene! Following extracellular...

...fragment Constant rate of p53 tetramerization in response to DNA damage controls the p53 response. Gaglia et...

...includes interactive maps for the Ras, mTor, and p53 pathways. The curation project continues to evolve...

... epitope tags into the endogenous alleles of the p53 and PTEN tumor suppressor genes in human cells (Kim...

...miRNA plasmid sequence. (A) Plasmid sequence from pLVUHshp53 (Addgene plasmid #11653). Full shRNA sequence...