A Look Back at One Year of Plasmid Sharing for COVID-19 Research
Type
Blog Post
Published
July 12, 2021, 1:15 p.m.
... for SARS-CoV-2 spike pseudotyping, visit the SARS-CoV-2 Pseudotyped Virus collection page.
SARS-CoV-2...reaction to detect SARS-CoV-2 nucleic acids.
Mammalian targets
During the 2003 SARS outbreak, Hyeryun ...functional receptor for SARS-CoV. The lab also found that cathepsins play a role in SARS-CoV infection and ...inhibitors of SARS-CoV-2 entry and become upregulated during viral infection.
Expression of SARS-CoV-2 viral...reached labs in over 75 countries.
Figure 1: SARS-CoV-2 proteins and other components. Image from ...labs.
Spike protein, variants, and pseudotyping
The SARS-CoV-2 virus depends on its spike protein to bind...and reagents for pseudotyping lentivirus with the SARS-CoV-2 spike protein. They deposited the plasmids...