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We narrowed to 14 results for: zan

Showing: 1 - 14 of 14 results
  1. CRISPR 101: Targeting Non-Coding RNAs with CRISPR/Cas9

    Type
    Blog Post
    Published
    Nov. 14, 2024, 2:15 p.m.
    ... and/or promoters to knock out lncRNA function (Hazan and Bester 2021; Zibitt et al. 2021). Mutating splice...inserted to disrupt the transcription of the ncRNA (Hazan and Bester 2021). For example, inserting a polyadenylation...polyadenylation (spA) signal. Figure and caption adapted from Hazan and Bester 2021.    Alternative CRISPR systems...chromatin structures or other local genomic elements (Hazan and Bester 2021). Other Cas variants Another option...337(6096):816-821. doi:10.1126/science.1225829  Hazan J, Bester AC. CRISPR-Based Approaches for the High-Throughput...
  2. Viral Vectors 101: Systemic Capsids

    Type
    Blog Post
    Published
    Oct. 12, 2023, 1:15 p.m.
    ...astrocytes Mice, marmosets Unknown Goertsen, Flytzanis, et al., 2022 AAV.CAP-B10 CNS: balanced ...marmosets Unknown Brown et al, 2021 Goertsen, Flytzanis, et al., 2022 Jang et al, 2023 AAV.CAP-Mac... transduction in off-target organs (Goertsen, Flytzanis, et al., 2022). AAV-PHP.N specifically transduces...doi.org/10.1038/s41467-023-38582-7 Chuapoco, M. R., Flytzanis, N. C., Goeden, N., Christopher Octeau, J., Roxas...https://doi.org/10.1038/nbt.3440 Goertsen, D., Flytzanis, N. C., Goeden, N., Chuapoco, M. R., Cummins, .../s41593-021-00969-4 Goertsen, D., Goeden, N., Flytzanis, N. C., & Gradinaru, V. (2022). Targeting the ...
  3. Hot Plasmids February 2024

    Type
    Blog Post
    Published
    Feb. 20, 2024, 2:45 p.m.
    ... AAV.CAP-Mac. Image reproduced from Chuapoco, Flytzanis, Goeden, et al. 2023, under CC-BY license. ... AAV.CAP-Mac plasmid here!   Chuapoco, M.R., Flytzanis, N.C., Goeden, N. et al. Adeno-associated viral...
  4. RNA Interference in Plant Biology: New Tools for an Old Favorite

    Type
    Blog Post
    Published
    Oct. 27, 2020, 1:15 p.m.
    ...bryophyte Physcomitrium (Physcomitrella) patens (Bezanilla et al., 2005; Nakaoka et al., 2012).     A new...cellular and multicellular scale.     References Bezanilla M, Perroud P ‐F., Pan A, Klueh P, Quatrano RS ...
  5. Lentiviral Vector Uses and Overview

    Type
    Blog Post
    Published
    May 19, 2016, 2:30 p.m.
    ...activation after gene therapy of human β-thalassaemia. Cavazzana-Calvo M, Payen E, Negre O, Wang G, Hehir K, Fusil...
  6. Plasmids 101: Control Plasmids

    Type
    Blog Post
    Published
    April 9, 2015, 3:29 p.m.
    ...may impose some limitations and you should be cognizant of these when interpreting your results. The key...
  7. Antibody Validation for Flow Cytometry

    Type
    Blog Post
    Published
    Sept. 10, 2024, 1:15 p.m.
    ...., McKeever, P. M., Kumar, R., Schwartz, J., Kolahdouzan, M., Chen, C. X., You, Z., Benaliouad, F., Gileadi...
  8. Deep Dive: qPCR

    Type
    Blog Post
    Published
    Sept. 29, 2022, 1:15 p.m.
    ...indicating 2 amplicons. Image credits (respectively): Zuzanna K. Filutowska; Selma, 2019; Trampuz, 2003. ...
Showing: 1 - 14 of 14 results