CRISPR Guide
Type
Guide
...Plasmids: CRISPR transposases CRISPR Recombinases and Integrases Recombinases, and their subfamily integrases...mechanisms, including transposons, integrases, and recombinases, with Cas enzymes. CRISPR Transposases Transposon... large scale edits. These proteins, like Cre recombinase or phage derived serine integrases, insert donor...lab , pairs prime editing with a large serine recombinase (LSR). A prime editor is used to install the ...evoBxb1 or eeBxb1 are evolved versions of the recombinase with improved integration efficiencies in mammalian...& Hsu, P. D. (2022). Systematic discovery of recombinases for efficient integration of large DNA sequences...locus. Chromosome painting requires delivery of hundreds of gRNAs with target sites throughout the chromosome...