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p4489 Flag-betaTrCP Citations (18)

Originally described in: Harnessing the ubiquitination machinery to target the degradation of specific cellular proteins.
Zhou P, Bogacki R, McReynolds L, Howley PM Mol Cell. 2000 Sep . 6(3):751-6.
PubMed Journal

Articles Citing p4489 Flag-betaTrCP

MAGUK-controlled ubiquitination of CARMA1 modulates lymphocyte NF-kappaB activity. Moreno-Garcia ME, Sommer K, Shinohara H, Bandaranayake AD, Kurosaki T, Rawlings DJ. Mol Cell Biol. 2010 Feb;30(4):922-34. doi: 10.1128/MCB.01129-09. Epub 2009 Dec 14. PubMed
Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle. Tudzarova S, Colombo SL, Stoeber K, Carcamo S, Williams GH, Moncada S. Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5278-83. doi: 10.1073/pnas.1102247108. Epub 2011 Mar 14. PubMed
The p97-Ufd1-Npl4 ATPase complex ensures robustness of the G2/M checkpoint by facilitating CDC25A degradation. Riemer A, Dobrynin G, Dressler A, Bremer S, Soni A, Iliakis G, Meyer H. Cell Cycle. 2014;13(6):919-27. doi: 10.4161/cc.27779. Epub 2014 Jan 15. PubMed
Structure, Dynamics and Functionality of Tankyrase Inhibitor-induced Degradasomes. Thorvaldsen TE, Pedersen NM, Wenzel EM, Schultz SW, Brech A, Liestol K, Waaler J, Krauss S, Stenmark H. Mol Cancer Res. 2015 Jun 29. pii: molcanres.0125.2015. PubMed
beta-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis. Cai J, Maitra A, Anders RA, Taketo MM, Pan D. Genes Dev. 2015 Jul 15;29(14):1493-506. doi: 10.1101/gad.264515.115. Epub 2015 Jul 20. PubMed
A High-Throughput Cell-Based Screen Identified a 2-[(E)-2-Phenylvinyl]-8-Quinolinol Core Structure That Activates p53. Bechill J, Zhong R, Zhang C, Solomaha E, Spiotto MT. PLoS One. 2016 Apr 28;11(4):e0154125. doi: 10.1371/journal.pone.0154125. eCollection 2016. PubMed
Comparative Proteomics Reveals Strain-Specific beta-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex. Ding S, Mooney N, Li B, Kelly MR, Feng N, Loktev AV, Sen A, Patton JT, Jackson PK, Greenberg HB. PLoS Pathog. 2016 Oct 5;12(10):e1005929. doi: 10.1371/journal.ppat.1005929. eCollection 2016 Oct. PubMed
E3 Ligase SCFbetaTrCP-induced DYRK1A Protein Degradation Is Essential for Cell Cycle Progression in HEK293 Cells. Liu Q, Tang Y, Chen L, Liu N, Lang F, Liu H, Wang P, Sun X. J Biol Chem. 2016 Dec 16;291(51):26399-26409. Epub 2016 Nov 2. PubMed
The nonreceptor tyrosine kinase c-Src attenuates SCF(beta-TrCP) E3-ligase activity abrogating Taz proteasomal degradation. Shanzer M, Adler J, Ricardo-Lax I, Reuven N, Shaul Y. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1678-1683. doi: 10.1073/pnas.1610223114. Epub 2017 Feb 1. PubMed
beta-transducin repeat-containing E3 ubiquitin protein ligase inhibits migration, invasion and proliferation of glioma cells. Liang J, Wang WF, Xie S, Zhang XL, Qi WF, Zhou XP, Hu JX, Shi Q, Yu RT. Oncol Lett. 2017 Sep;14(3):3131-3135. doi: 10.3892/ol.2017.6533. Epub 2017 Jul 7. PubMed
ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma. Linares JF, Cordes T, Duran A, Reina-Campos M, Valencia T, Ahn CS, Castilla EA, Moscat J, Metallo CM, Diaz-Meco MT. Cell Metab. 2017 Dec 5;26(6):817-829.e6. doi: 10.1016/j.cmet.2017.09.001. Epub 2017 Oct 5. PubMed
IKKbeta is a beta-catenin kinase that regulates mesenchymal stem cell differentiation. Sui Y, Liu Z, Park SH, Thatcher SE, Zhu B, Fernandez JP, Molina H, Kern PA, Zhou C. JCI Insight. 2018 Jan 25;3(2). pii: 96660. doi: 10.1172/jci.insight.96660. eCollection 2018 Jan 25. PubMed
Non-canonical activation of hedgehog in prostate cancer cells mediated by the interaction of transcriptionally active androgen receptor proteins with Gli3. Li N, Truong S, Nouri M, Moore J, Al Nakouzi N, Lubik AA, Buttyan R. Oncogene. 2018 Apr;37(17):2313-2325. doi: 10.1038/s41388-017-0098-7. Epub 2018 Feb 12. PubMed
Coordinated regulation of the dorsal-ventral and anterior-posterior patterning of Xenopus embryos by the BTB/POZ zinc finger protein Zbtb14. Takebayashi-Suzuki K, Konishi H, Miyamoto T, Nagata T, Uchida M, Suzuki A. Dev Growth Differ. 2018 Apr;60(3):158-173. doi: 10.1111/dgd.12431. PubMed
Protein kinase CK2 activation is required for transforming growth factor beta-induced epithelial-mesenchymal transition. Kim S, Ham S, Yang K, Kim K. Mol Oncol. 2018 Oct;12(10):1811-1826. doi: 10.1002/1878-0261.12378. Epub 2018 Sep 21. PubMed
RNA-binding protein CELF6 is cell cycle regulated and controls cancer cell proliferation by stabilizing p21. Liu G, Zhang Q, Xia L, Shi M, Cai J, Zhang H, Li J, Lin G, Xie W, Zhang Y, Xu N. Cell Death Dis. 2019 Sep 18;10(10):688. doi: 10.1038/s41419-019-1927-0. PubMed
Anti-cancer potential of persimmon (Diospyros kaki) leaves via the PDGFR-Rac-JNK pathway. Kim HS, Suh JS, Jang YK, Ahn SH, Raja G, Kim JC, Jung Y, Jung SH, Kim TJ. Sci Rep. 2020 Oct 22;10(1):18119. doi: 10.1038/s41598-020-75140-3. PubMed
WBP2 promotes BTRC mRNA stability to drive migration and invasion in triple-negative breast cancer via NF-kappaB activation. Lim YX, Lin H, Chu T, Lim YP. Mol Oncol. 2022 Jan;16(2):422-446. doi: 10.1002/1878-0261.13048. Epub 2021 Aug 12. PubMed

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