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pXR002: EF1a-dCasRx-2A-EGFP Citations (11)

Originally described in: Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors.
Konermann S, Lotfy P, Brideau NJ, Oki J, Shokhirev MN, Hsu PD Cell. 2018 Mar 8. pii: S0092-8674(18)30207-1. doi: 10.1016/j.cell.2018.02.033.
PubMed Journal

Articles Citing pXR002: EF1a-dCasRx-2A-EGFP

Articles
Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d. Zhang C, Konermann S, Brideau NJ, Lotfy P, Wu X, Novick SJ, Strutzenberg T, Griffin PR, Hsu PD, Lyumkis D. Cell. 2018 Sep 20;175(1):212-223.e17. doi: 10.1016/j.cell.2018.09.001. PubMed
CRISPR-Cas13d mediates robust RNA virus interference in plants. Mahas A, Aman R, Mahfouz M. Genome Biol. 2019 Dec 2;20(1):263. doi: 10.1186/s13059-019-1881-2. PubMed
CRISPR-assisted detection of RNA-protein interactions in living cells. Yi W, Li J, Zhu X, Wang X, Fan L, Sun W, Liao L, Zhang J, Li X, Ye J, Chen F, Taipale J, Chan KM, Zhang L, Yan J. Nat Methods. 2020 Jun 22. pii: 10.1038/s41592-020-0866-0. doi: 10.1038/s41592-020-0866-0. PubMed

Associated Plasmids

RNA m(6)A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability. Xiong F, Wang R, Lee JH, Li S, Chen SF, Liao Z, Hasani LA, Nguyen PT, Zhu X, Krakowiak J, Lee DF, Han L, Tsai KL, Liu Y, Li W. Cell Res. 2021 Aug;31(8):861-885. doi: 10.1038/s41422-021-00515-8. Epub 2021 Jun 9. PubMed
Efficient Inhibition of HIV Using CRISPR/Cas13d Nuclease System. Nguyen H, Wilson H, Jayakumar S, Kulkarni V, Kulkarni S. Viruses. 2021 Sep 16;13(9). pii: v13091850. doi: 10.3390/v13091850. PubMed
Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex. Han C, Sun LY, Luo XQ, Pan Q, Sun YM, Zeng ZC, Chen TQ, Huang W, Fang K, Wang WT, Chen YQ. Cell Rep. 2022 Mar 29;38(13):110421. doi: 10.1016/j.celrep.2022.110421. PubMed
Negative autoregulation mitigates collateral RNase activity of repeat-targeting CRISPR-Cas13d in mammalian cells. Kelley CP, Haerle MC, Wang ET. Cell Rep. 2022 Aug 16;40(7):111226. doi: 10.1016/j.celrep.2022.111226. PubMed
A single N6-methyladenosine site regulates lncRNA HOTAIR function in breast cancer cells. Porman AM, Roberts JT, Duncan ED, Chrupcala ML, Levine AA, Kennedy MA, Williams MM, Richer JK, Johnson AM. PLoS Biol. 2022 Nov 28;20(11):e3001885. doi: 10.1371/journal.pbio.3001885. eCollection 2022 Nov. PubMed
METTL3-Mediated m6A Modification Controls Splicing Factor Abundance and Contributes to Aggressive CLL. Wu Y, Jin M, Fernandez M, Hart KL, Liao A, Ge X, Fernandes SM, McDonald T, Chen Z, Roth D, Ghoda LY, Marcucci G, Kalkum M, Pillai RK, Danilov AV, Li JJ, Chen J, Brown JR, Rosen ST, Siddiqi T, Wang L. Blood Cancer Discov. 2023 May 1;4(3):228-245. doi: 10.1158/2643-3230.BCD-22-0156. PubMed
Deep screening of proximal and distal splicing-regulatory elements in a native sequence context. Recinos Y, Ustianenko D, Yeh YT, Wang X, Jacko M, Yesantharao LV, Wu Q, Zhang C. bioRxiv [Preprint]. 2023 Aug 21:2023.08.21.554109. doi: 10.1101/2023.08.21.554109. PubMed
Noncoding function of super enhancer derived mRNA in modulating neighboring gene expression and TAD interaction. Xie B, Dean A. bioRxiv [Preprint]. 2023 Dec 5:2023.12.05.570115. doi: 10.1101/2023.12.05.570115. PubMed

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