ppyCAG_RNaseH1_WKKD Citations (11)
Originally described in: R-ChIP Using Inactive RNase H Reveals Dynamic Coupling of R-loops with Transcriptional Pausing at Gene Promoters.Chen L, Chen JY, Zhang X, Gu Y, Xiao R, Shao C, Tang P, Qian H, Luo D, Li H, Zhou Y, Zhang DE, Fu XD Mol Cell. 2017 Nov 16;68(4):745-757.e5. doi: 10.1016/j.molcel.2017.10.008. Epub 2017 Nov 2. PubMed Journal
Articles Citing ppyCAG_RNaseH1_WKKD
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BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation.
Edwards DS, Maganti R, Tanksley JP, Luo J, Park JJH, Balkanska-Sinclair E, Ling J, Floyd SR.
Cell Rep. 2020 Sep 22;32(12):108166. doi: 10.1016/j.celrep.2020.108166.
PubMed
Associated Plasmids |
| NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer. Guo H, Golczer G, Wittner BS, Langenbucher A, Zachariah M, Dubash TD, Hong X, Comaills V, Burr R, Ebright RY, Horwitz E, Vuille JA, Hajizadeh S, Wiley DF, Reeves BA, Zhang JM, Niederhoffer KL, Lu C, Wesley B, Ho U, Nieman LT, Toner M, Vasudevan S, Zou L, Mostoslavsky R, Maheswaran S, Lawrence MS, Haber DA. Mol Cell. 2021 Oct 7;81(19):4041-4058.e15. doi: 10.1016/j.molcel.2021.09.016. PubMed |
| DNA double-strand break-derived RNA drives TIRR/53BP1 complex dissociation. Ketley RF, Battistini F, Alagia A, Mondielli C, Iehl F, Balikci E, Huber KVM, Orozco M, Gullerova M. Cell Rep. 2022 Oct 25;41(4):111526. doi: 10.1016/j.celrep.2022.111526. PubMed |
| TERRA stability is regulated by RALY and polyadenylation in a telomere-specific manner. Savoca V, Rivosecchi J, Gaiatto A, Rossi A, Mosca R, Gialdini I, Zubovic L, Tebaldi T, Macchi P, Cusanelli E. Cell Rep. 2023 Apr 25;42(4):112406. doi: 10.1016/j.celrep.2023.112406. Epub 2023 Apr 14. PubMed |
| EWSR1 maintains centromere identity. Kitagawa R, Niikura Y, Becker A, Houghton PJ, Kitagawa K. Cell Rep. 2023 Jun 27;42(6):112568. doi: 10.1016/j.celrep.2023.112568. Epub 2023 May 25. PubMed |
| SF3B1 mutation and ATM deletion codrive leukemogenesis via centromeric R-loop dysregulation. Cusan M, Shen H, Zhang B, Liao A, Yang L, Jin M, Fernandez M, Iyer P, Wu Y, Hart K, Gutierrez C, Nik S, Pruett-Miller SM, Stark J, Obeng EA, Bowman TV, Wu CJ, Lin RJ, Wang L. J Clin Invest. 2023 Sep 1;133(17):e163325. doi: 10.1172/JCI163325. PubMed |
| Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops. Ma TS, Worth KR, Maher C, Ng N, Beghe C, Gromak N, Rose AM, Hammond EM. Nucleic Acids Res. 2023 Nov 27;51(21):11584-11599. doi: 10.1093/nar/gkad858. PubMed |
| Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality. Lin P, Lourenco C, Cruickshank J, Palomero L, van Leeuwen JE, Tong AHY, Chan K, El Ghamrasni S, Pujana MA, Cescon DW, Moffat J, Penn LZ. Cancer Res. 2023 Dec 15;83(24):4015-4029. doi: 10.1158/0008-5472.CAN-22-2948. PubMed |
| Human DNA topoisomerase I poisoning causes R loop-mediated genome instability attenuated by transcription factor IIS. Duardo RC, Marinello J, Russo M, Morelli S, Pepe S, Guerra F, Gomez-Gonzalez B, Aguilera A, Capranico G. Sci Adv. 2024 May 24;10(21):eadm8196. doi: 10.1126/sciadv.adm8196. Epub 2024 May 24. PubMed |
| Comprehensive interrogation of synthetic lethality in the DNA damage response. Fielden J, Siegner SM, Gallagher DN, Schroder MS, Dello Stritto MR, Lam S, Kobel L, Schlapansky MF, Jackson SP, Cejka P, Jost M, Corn JE. Nature. 2025 Apr;640(8060):1093-1102. doi: 10.1038/s41586-025-08815-4. Epub 2025 Apr 9. PubMed |
| Interferon-dependent R-loop induction by Zika virus contributes to growth attenuation. Zhao Y, Metzler AD, Li Y, Urlich P, Wang Y, Gilbert DM, Yao B, Tang H. PNAS Nexus. 2025 May 7;4(5):pgaf147. doi: 10.1093/pnasnexus/pgaf147. eCollection 2025 May. PubMed |
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