Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more


pKH3-human RSK1 Citations (10)

Originally described in: Characterization of regulatory events associated with membrane targeting of p90 ribosomal S6 kinase 1.
Richards SA, Dreisbach VC, Murphy LO, Blenis J Mol Cell Biol. 2001 Nov . 21(21):7470-80.
PubMed Journal

Articles Citing pKH3-human RSK1

Yersinia virulence factor YopM induces sustained RSK activation by interfering with dephosphorylation. Hentschke M, Berneking L, Belmar Campos C, Buck F, Ruckdeschel K, Aepfelbacher M. PLoS One. 2010 Oct 5;5(10). pii: e13165. doi: 10.1371/journal.pone.0013165. PubMed
Tumor necrosis factor receptor-associated factor family protein 2 is a key mediator of the epidermal growth factor-induced ribosomal S6 kinase 2/cAMP-responsive element-binding protein/Fos protein signaling pathway. Peng C, Zhu F, Wen W, Yao K, Li S, Zykova T, Liu K, Li X, Ma WY, Bode AM, Dong Z. J Biol Chem. 2012 Jul 27;287(31):25881-92. doi: 10.1074/jbc.M112.359521. Epub 2012 Jun 8. PubMed
Phosphorylation of KIBRA by the extracellular signal-regulated kinase (ERK)-ribosomal S6 kinase (RSK) cascade modulates cell proliferation and migration. Yang S, Ji M, Zhang L, Chen Y, Wennmann DO, Kremerskothen J, Dong J. Cell Signal. 2014 Feb;26(2):343-51. doi: 10.1016/j.cellsig.2013.11.012. Epub 2013 Nov 19. PubMed
Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells. Berneking L, Schnapp M, Rumm A, Trasak C, Ruckdeschel K, Alawi M, Grundhoff A, Kikhney AG, Koch-Nolte F, Buck F, Perbandt M, Betzel C, Svergun DI, Hentschke M, Aepfelbacher M. PLoS Pathog. 2016 Jun 14;12(6):e1005660. doi: 10.1371/journal.ppat.1005660. eCollection 2016 Jun. PubMed
Proteome-wide analysis of phospho-regulated PDZ domain interactions. Sundell GN, Arnold R, Ali M, Naksukpaiboon P, Orts J, Guntert P, Chi CN, Ivarsson Y. Mol Syst Biol. 2018 Aug 20;14(8):e8129. doi: 10.15252/msb.20178129. PubMed
FLT3-ITD Activates RSK1 to Enhance Proliferation and Survival of AML Cells by Activating mTORC1 and eIF4B Cooperatively with PIM or PI3K and by Inhibiting Bad and BIM. Watanabe D, Nogami A, Okada K, Akiyama H, Umezawa Y, Miura O. Cancers (Basel). 2019 Nov 20;11(12). pii: cancers11121827. doi: 10.3390/cancers11121827. PubMed
Adaptive RSK-EphA2-GPRC5A signaling switch triggers chemotherapy resistance in ovarian cancer. Moyano-Galceran L, Pietila EA, Turunen SP, Corvigno S, Hjerpe E, Bulanova D, Joneborg U, Alkasalias T, Miki Y, Yashiro M, Chernenko A, Jukonen J, Singh M, Dahlstrand H, Carlson JW, Lehti K. EMBO Mol Med. 2020 Apr 7;12(4):e11177. doi: 10.15252/emmm.201911177. Epub 2020 Mar 2. PubMed
Plakophilin 3 phosphorylation by ribosomal S6 kinases supports desmosome assembly. Muller L, Rietscher K, Keil R, Neuholz M, Hatzfeld M. J Cell Sci. 2020 Apr 16;133(8). pii: jcs.238295. doi: 10.1242/jcs.238295. PubMed
Histone Deacetylase 9 Activates IKK to Regulate Atherosclerotic Plaque Vulnerability. Asare Y, Campbell-James TA, Bokov Y, Yu LL, Prestel M, El Bounkari O, Roth S, Megens RTA, Straub T, Thomas K, Yan G, Schneider M, Ziesch N, Tiedt S, Silvestre-Roig C, Braster Q, Huang Y, Schneider M, Malik R, Haffner C, Liesz A, Soehnlein O, Bernhagen J, Dichgans M. Circ Res. 2020 Aug 28;127(6):811-823. doi: 10.1161/CIRCRESAHA.120.316743. Epub 2020 Jun 17. PubMed
ERK phosphorylation disrupts the intramolecular interaction of capicua to promote cytoplasmic translocation of capicua and tumor growth. Park J, Park GY, Lee J, Park J, Kim S, Kim E, Park SY, Yoon JH, Lee Y. Front Mol Biosci. 2022 Dec 22;9:1030725. doi: 10.3389/fmolb.2022.1030725. eCollection 2022. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.