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ODD-Luciferase-pcDNA3 Citations (14)

Originally described in: Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production.
Safran M, Kim WY, O'Connell F, Flippin L, Gunzler V, Horner JW, Depinho RA, Kaelin WG Proc Natl Acad Sci U S A. 2006 Jan 3. 103(1):105-10.
PubMed Journal

Articles Citing ODD-Luciferase-pcDNA3

HIF-1alpha and HIF-2alpha degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc. Fujita N, Chiba K, Shapiro IM, Risbud MV. J Bone Miner Res. 2012 Feb;27(2):401-12. doi: 10.1002/jbmr.538. PubMed
Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells: role of Hsp70 in HIF-1alpha degradation. Gogate SS, Fujita N, Skubutyte R, Shapiro IM, Risbud MV. J Bone Miner Res. 2012 May;27(5):1106-17. doi: 10.1002/jbmr.1571. PubMed
Gramicidin A blocks tumor growth and angiogenesis through inhibition of hypoxia-inducible factor in renal cell carcinoma. David JM, Owens TA, Inge LJ, Bremner RM, Rajasekaran AK. Mol Cancer Ther. 2014 Apr;13(4):788-99. doi: 10.1158/1535-7163.MCT-13-0891. Epub 2014 Feb 3. PubMed
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid. Colegio OR, Chu NQ, Szabo AL, Chu T, Rhebergen AM, Jairam V, Cyrus N, Brokowski CE, Eisenbarth SC, Phillips GM, Cline GW, Phillips AJ, Medzhitov R. Nature. 2014 Sep 25;513(7519):559-63. doi: 10.1038/nature13490. Epub 2014 Jul 13. PubMed
Intermediary metabolite precursor dimethyl-2-ketoglutarate stabilizes hypoxia-inducible factor-1alpha by inhibiting prolyl-4-hydroxylase PHD2. Hou P, Kuo CY, Cheng CT, Liou JP, Ann DK, Chen Q. PLoS One. 2014 Nov 24;9(11):e113865. doi: 10.1371/journal.pone.0113865. eCollection 2014. PubMed
Stearic acid induces proinflammatory cytokine production partly through activation of lactate-HIF1alpha pathway in chondrocytes. Miao H, Chen L, Hao L, Zhang X, Chen Y, Ruan Z, Liang H. Sci Rep. 2015 Aug 14;5:13092. doi: 10.1038/srep13092. PubMed
Glutamine activates STAT3 to control cancer cell proliferation independently of glutamine metabolism. Cacace A, Sboarina M, Vazeille T, Sonveaux P. Oncogene. 2016 Oct 17. doi: 10.1038/onc.2016.364. PubMed
Collagen prolyl 4-hydroxylase 1 is essential for HIF-1alpha stabilization and TNBC chemoresistance. Xiong G, Stewart RL, Chen J, Gao T, Scott TL, Samayoa LM, O'Connor K, Lane AN, Xu R. Nat Commun. 2018 Oct 26;9(1):4456. doi: 10.1038/s41467-018-06893-9. PubMed
KLF4(K409Q)-mutated meningiomas show enhanced hypoxia signaling and respond to mTORC1 inhibitor treatment. von Spreckelsen N, Waldt N, Poetschke R, Kesseler C, Dohmen H, Jiao HK, Nemeth A, Schob S, Scherlach C, Sandalcioglu IE, Deckert M, Angenstein F, Krischek B, Stavrinou P, Timmer M, Remke M, Kirches E, Goldbrunner R, Chiocca EA, Huettelmaier S, Acker T, Mawrin C. Acta Neuropathol Commun. 2020 Apr 3;8(1):41. doi: 10.1186/s40478-020-00912-x. PubMed
Targeting Hypoxia Sensitizes TNBC to Cisplatin and Promotes Inhibition of Both Bulk and Cancer Stem Cells. Sulaiman A, McGarry S, Chambers J, Al-Kadi E, Phan A, Li L, Mediratta K, Dimitroulakos J, Addison C, Li X, Wang L. Int J Mol Sci. 2020 Aug 12;21(16). pii: ijms21165788. doi: 10.3390/ijms21165788. PubMed
Pharmacological Regulation of Tumor Hypoxia in Model Murine Tumors and Spontaneous Canine Tumors. Benej M, Wu J, Kreamer M, Kery M, Corrales-Guerrero S, Papandreou I, Williams TM, Li Z, Graves EE, Selmic LE, Denko NC. Cancers (Basel). 2021 Apr 3;13(7). pii: cancers13071696. doi: 10.3390/cancers13071696. PubMed
The Natural Product beta-Escin Targets Cancer and Stromal Cells of the Tumor Microenvironment to Inhibit Ovarian Cancer Metastasis. Kenny HA, Hart PC, Kordylewicz K, Lal M, Shen M, Kara B, Chen YJ, Grassl N, Alharbi Y, Pattnaik BR, Watters KM, Patankar MS, Ferrer M, Lengyel E. Cancers (Basel). 2021 Aug 4;13(16). pii: cancers13163931. doi: 10.3390/cancers13163931. PubMed
Adipocytes reprogram cancer cell metabolism by diverting glucose towards glycerol-3-phosphate thereby promoting metastasis. Mukherjee A, Bezwada D, Greco F, Zandbergen M, Shen T, Chiang CY, Tasdemir M, Fahrmann J, Grapov D, La Frano MR, Vu HS, Faubert B, Newman JW, McDonnell LA, Nezi L, Fiehn O, DeBerardinis RJ, Lengyel E. Nat Metab. 2023 Sep;5(9):1563-1577. doi: 10.1038/s42255-023-00879-8. Epub 2023 Aug 31. PubMed
Oxidized Low-Density Lipoprotein Accumulation Suppresses Glycolysis and Attenuates the Macrophage Inflammatory Response by Diverting Transcription from the HIF-1alpha to the Nrf2 Pathway. Ting KKY, Yu P, Dow R, Floro E, Ibrahim H, Scipione CA, Hyduk SJ, Polenz CK, Zaslaver O, Karmaus PWF, Fessler MB, Rost HL, Ohh M, Tsai S, Winer DA, Woo M, Rocheleau J, Jongstra-Bilen J, Cybulsky MI. J Immunol. 2023 Nov 15;211(10):1561-1577. doi: 10.4049/jimmunol.2300293. PubMed

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