Skip to main content
Addgene

Anti-Nav1.8 Na+ channel [N134/12R]
(Antibody #192035)

Ordering

Item Catalog # Description Quantity Price (USD)
Recombinant Antibody 192035-rAb 100 µg of purified recombinant antibody $250 *
Recombinant Antibody trial size 192035-rAb.T 20 µg of purified recombinant antibody $85 *

* Log in to view industry pricing.

Features

Production & Usage

  • Production Plasmid
    Anti-Nav1.8 Na+ channel [N134/12R]
  • Purification
    Purified from cell culture supernatant using Protein A or Protein G affinity columns followed by a buffer exchange with centrifugal columns.
  • Storage Buffer
    PBS + 1 mM sodium azide

Delivery

  • Concentration
    0.9–1.1 mg/mL
  • Storage
    Upon receipt, prepare single use aliquots and store at -20 °C until use. Avoid multiple freeze thaw cycles.
  • Shipment
    Blue ice or room temp

Resource Information

  • Persistent Resource Identifier
    RRID:AB_2916236

Terms and Licenses

Target Antigen

Protein Sodium channel protein type 10 subunit alpha
Antigen Description Amino acids 1724–1956 (cytoplasmic C-terminus) of rat Nav1.8
Antigen Amino Acid Sequence
ENFNVATEESTEPLSEDDFDMFYETWEKFDPEATQFIAFSALSDFADTLSGPLRIPKPNQNILIQMDLPLVPGDKIHCLDILFAFTKNVLGESGELDSLKTNMEEKFMATNLSKASYEPIATTLRWKQEDLSATVIQKAYRSYMLHRSLTLSNTLHVPRAEEDGVSLPGEGYVTFMANSGLPDKSETASATSFPPSYDSVTRGLSDRANINPSSSMQNEDEVAAKEGNSPGPQ
Species R. norvegicus (rat)
Additional Species Reactivity H. sapiens (human),  M. musculus (mouse)
Gene Scn10a
Alternative Names
  • Peripheral nerve sodium channel 3 (PN3)
  • Sensory neuron sodium channel
  • Sodium channel protein type X subunit alpha
  • Voltage-gated sodium channel subunit alpha Nav1.8
External References

Applications (2)

Clear filters

Immunohistochemistry

1 image
Immunohistochemistry image by Dr. Joel Black, Dr. Sulayman Dib-Hajj and Dr. Steve Waxman, Yale University
Submitted By: Dr. Joel Black, Dr. Sulayman Dib-Hajj and Dr. Steve Waxman, Yale University
Antibody Type
Hybridoma
Sample Species
R. norvegicus (rat)
Result
Pass
1 image
Immunohistochemistry image by Dr. Joel Black, Dr. Sulayman Dib-Hajj and Dr. Steve Waxman, Yale University Knockout validation
Submitted By: Dr. Joel Black, Dr. Sulayman Dib-Hajj and Dr. Steve Waxman, Yale University
Antibody Type
Hybridoma
Sample Species
M. musculus (mouse)
Result
Pass

Depositor Comments

Does not react with Nav1.7
How to cite this antibody ( Back to top)

These antibodies were created by your colleagues. Please acknowledge the Principal Investigator, cite the article in which the antibodies were described, and include Addgene in the Materials and Methods of your future publications.

  • For your Materials & Methods section:

    Anti-Nav1.8 Na+ channel [N134/12R] - from James Trimmer (Addgene antibody # 192035 ; http://n2t.net/addgene:192035 ; RRID:AB_2916236)
  • For your References section:

    A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain. Andrews NP, Boeckman JX, Manning CF, Nguyen JT, Bechtold H, Dumitras C, Gong B, Nguyen K, van der List D, Murray KD, Engebrecht J, Trimmer JS. Elife. 2019 Jan 22;8. pii: 43322. doi: 10.7554/eLife.43322. 10.7554/eLife.43322 PubMed 30667360