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pEP4 E02S ET2K Citations (45)

Plasmid Article: Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
Yu J, Hu K, Smuga-Otto K, Tian S, Stewart R, Slukvin II, Thomson JA Science. 2009 Mar 26.
PubMed Journal

Articles Citing pEP4 E02S ET2K

A more efficient method to generate integration-free human iPS cells. Okita K, Matsumura Y, Sato Y, Okada A, Morizane A, Okamoto S, Hong H, Nakagawa M, Tanabe K, Tezuka KI, Shibata T, Kunisada T, Takahashi M, Takahashi J, Saji H, Yamanaka S. Nat Methods. 2011 May;8(5):409-12 PubMed

Associated Plasmids

Subtle changes to polymer structure and degradation mechanism enable highly effective nanoparticles for siRNA and DNA delivery to human brain cancer. Tzeng SY, Green JJ. Adv Healthc Mater. 2013 Mar;2(3):468-80. doi: 10.1002/adhm.201200257. Epub 2012 Sep 26. PubMed
An Efficient Non-viral Method to Generate Integration-Free Human iPS Cells from Cord Blood and Peripheral Blood Cells. Okita K, Yamakawa T, Matsumura Y, Sato Y, Amano N, Watanabe A, Goshima N, Yamanaka S. Stem Cells. 2012 Nov 29. doi: 10.1002/stem.1293. PubMed

Associated Plasmids

Integration-free induced pluripotent stem cells model genetic and neural developmental features of down syndrome etiology. Briggs JA, Sun J, Shepherd J, Ovchinnikov DA, Chung TL, Nayler SP, Kao LP, Morrow CA, Thakar NY, Soo SY, Peura T, Grimmond S, Wolvetang EJ. Stem Cells. 2013 Mar;31(3):467-78. doi: 10.1002/stem.1297. PubMed
A systematic evaluation of integration free reprogramming methods for deriving clinically relevant patient specific induced pluripotent stem (iPS) cells. Goh PA, Caxaria S, Casper C, Rosales C, Warner TT, Coffey PJ, Nathwani AC. PLoS One. 2013 Nov 26;8(11):e81622. doi: 10.1371/journal.pone.0081622. eCollection 2013. PubMed
Synaptic dysregulation in a human iPS cell model of mental disorders. Wen Z, Nguyen HN, Guo Z, Lalli MA, Wang X, Su Y, Kim NS, Yoon KJ, Shin J, Zhang C, Makri G, Nauen D, Yu H, Guzman E, Chiang CH, Yoritomo N, Kaibuchi K, Zou J, Christian KM, Cheng L, Ross CA, Margolis RL, Chen G, Kosik KS, Song H, Ming GL. Nature. 2014 Nov 20;515(7527):414-8. doi: 10.1038/nature13716. Epub 2014 Aug 17. PubMed
KLF4 N-terminal variance modulates induced reprogramming to pluripotency. Kim SI, Oceguera-Yanez F, Hirohata R, Linker S, Okita K, Yamada Y, Yamamoto T, Yamanaka S, Woltjen K. Stem Cell Reports. 2015 Apr 14;4(4):727-43. doi: 10.1016/j.stemcr.2015.02.004. Epub 2015 Mar 12. PubMed

Associated Plasmids

Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome. Jouni M, Si-Tayeb K, Es-Salah-Lamoureux Z, Latypova X, Champon B, Caillaud A, Rungoat A, Charpentier F, Loussouarn G, Baro I, Zibara K, Lemarchand P, Gaborit N. J Am Heart Assoc. 2015 Sep 1;4(9):e002159. doi: 10.1161/JAHA.115.002159. PubMed
Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia. Si-Tayeb K, Idriss S, Champon B, Caillaud A, Pichelin M, Arnaud L, Lemarchand P, Le May C, Zibara K, Cariou B. Dis Model Mech. 2016 Jan;9(1):81-90. doi: 10.1242/dmm.022277. Epub 2015 Nov 19. PubMed
Generation of Footprint-Free Induced Pluripotent Stem Cells from Human Fibroblasts Using Episomal Plasmid Vectors. Ovchinnikov DA, Sun J, Wolvetang EJ. Methods Mol Biol. 2015;1330:37-45. doi: 10.1007/978-1-4939-2848-4_4. PubMed
Non-integrating episomal plasmid-based reprogramming of human amniotic fluid stem cells into induced pluripotent stem cells in chemically defined conditions. Slamecka J, Salimova L, McClellan S, van Kelle M, Kehl D, Laurini J, Cinelli P, Owen L, Hoerstrup SP, Weber B. Cell Cycle. 2016;15(2):234-49. doi: 10.1080/15384101.2015.1121332. PubMed
Generation of iPSC line epiHUVEC from human umbilical vein endothelial cells. Matz P, Adjaye J. Stem Cell Res. 2015 Nov;15(3):581-3. doi: 10.1016/j.scr.2015.10.004. Epub 2015 Oct 14. PubMed
Integration-Free Reprogramming of Lamina Propria Progenitor Cells. Howard-Jones RA, Cheung OK, Glen A, Allen ND, Stephens P. J Dent Res. 2016 Jul;95(8):882-8. doi: 10.1177/0022034516637579. Epub 2016 Mar 18. PubMed
Episomal-based generation of an iPS cell line from human fetal foreskin fibroblasts. Matz P, Adjaye J. Stem Cell Res. 2016 Jan;16(1):67-9. doi: 10.1016/j.scr.2015.12.009. Epub 2015 Dec 17. PubMed
Episomal plasmid-based generation of induced pluripotent stem cells from fetal femur-derived human mesenchymal stromal cells. Megges M, Oreffo RO, Adjaye J. Stem Cell Res. 2016 Jan;16(1):128-32. doi: 10.1016/j.scr.2015.12.013. Epub 2015 Dec 28. PubMed
ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53. Ghouzzi VE, Bianchi FT, Molineris I, Mounce BC, Berto GE, Rak M, Lebon S, Aubry L, Tocco C, Gai M, Chiotto AM, Sgro F, Pallavicini G, Simon-Loriere E, Passemard S, Vignuzzi M, Gressens P, Di Cunto F. Cell Death Dis. 2016 Oct 27;7(10):e2440. doi: 10.1038/cddis.2016.266. PubMed
Induced pluripotent stem cells derived from human amnion in chemically defined conditions. Slamecka J, McClellan S, Wilk A, Laurini J, Manci E, Hoerstrup SP, Weber B, Owen L. Cell Cycle. 2018;17(3):330-347. doi: 10.1080/15384101.2017.1403690. Epub 2018 Feb 7. PubMed
Generation of Urine Cell-Derived Non-integrative Human iPSCs and iNSCs: A Step-by-Step Optimized Protocol. Cheng L, Lei Q, Yin C, Wang HY, Jin K, Xiang M. Front Mol Neurosci. 2017 Oct 30;10:348. doi: 10.3389/fnmol.2017.00348. eCollection 2017. PubMed
Interaction of iPSC-derived neural stem cells on poly(L-lactic acid) nanofibrous scaffolds for possible use in neural tissue engineering. Lin C, Liu C, Zhang L, Huang Z, Zhao P, Chen R, Pang M, Chen Z, He L, Luo C, Rong L, Liu B. Int J Mol Med. 2018 Feb;41(2):697-708. doi: 10.3892/ijmm.2017.3299. Epub 2017 Nov 30. PubMed
A novel human induced pluripotent stem cell blood-brain barrier model: Applicability to study antibody-triggered receptor-mediated transcytosis. Ribecco-Lutkiewicz M, Sodja C, Haukenfrers J, Haqqani AS, Ly D, Zachar P, Baumann E, Ball M, Huang J, Rukhlova M, Martina M, Liu Q, Stanimirovic D, Jezierski A, Bani-Yaghoub M. Sci Rep. 2018 Jan 30;8(1):1873. doi: 10.1038/s41598-018-19522-8. PubMed
Simultaneous reprogramming and gene editing of human fibroblasts. Howden SE, Thomson JA, Little MH. Nat Protoc. 2018 May;13(5):875-898. doi: 10.1038/nprot.2018.007. Epub 2018 Apr 5. PubMed
Zika virus crosses an in vitro human blood brain barrier model. Alimonti JB, Ribecco-Lutkiewicz M, Sodja C, Jezierski A, Stanimirovic DB, Liu Q, Haqqani AS, Conlan W, Bani-Yaghoub M. Fluids Barriers CNS. 2018 May 15;15(1):15. doi: 10.1186/s12987-018-0100-y. PubMed
Generation of an integration-free iPSC line(SYSUi001-A) from a sporadic Alzheimer's disease patient. Wei R, Han H, Ye M, He L, Lei Q, Zhou T, Cai X, Li Z. Stem Cell Res. 2019 Mar;35:101375. doi: 10.1016/j.scr.2018.101375. Epub 2018 Dec 18. PubMed
Distinctive Krebs cycle remodeling in iPSC-derived neural and mesenchymal stem cells. Benlamara S, Aubry L, Fabregue J, Benit P, Rustin P, Rak M. Biochem Biophys Res Commun. 2019 Apr 9;511(3):658-664. doi: 10.1016/j.bbrc.2019.02.033. Epub 2019 Feb 27. PubMed
The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line. Howden S, Hosseini Far H, Motazedian A, Elefanty AG, Stanley EG, Lamande SR, Bateman JF. Stem Cell Res. 2019 Jul;38:101453. doi: 10.1016/j.scr.2019.101453. Epub 2019 May 4. PubMed
Epigenetic reprogramming of primary pancreatic cancer cells counteracts their in vivo tumourigenicity. Khoshchehreh R, Totonchi M, Carlos Ramirez J, Torres R, Baharvand H, Aicher A, Ebrahimi M, Heeschen C. Oncogene. 2019 Aug;38(34):6226-6239. doi: 10.1038/s41388-019-0871-x. Epub 2019 Jul 15. PubMed
Induced pluripotent stem cells-derived neurons from patients with Friedreich ataxia exhibit differential sensitivity to resveratrol and nicotinamide. Georges P, Boza-Moran MG, Gide J, Peche GA, Foret B, Bayot A, Rustin P, Peschanski M, Martinat C, Aubry L. Sci Rep. 2019 Oct 10;9(1):14568. doi: 10.1038/s41598-019-49870-y. PubMed
Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi003-A) from a Wilson's disease patient harboring a homozygous R778L mutation in ATP7B gene. Zhang J, Wei L, Chen D, Feng L, Wu C, Wang R, Li X. Stem Cell Res. 2019 Dec;41:101664. doi: 10.1016/j.scr.2019.101664. Epub 2019 Nov 21. PubMed
The FGF, TGFbeta and WNT axis Modulate Self-renewal of Human SIX2(+) Urine Derived Renal Progenitor Cells. Rahman MS, Wruck W, Spitzhorn LS, Nguyen L, Bohndorf M, Martins S, Asar F, Ncube A, Erichsen L, Graffmann N, Adjaye J. Sci Rep. 2020 Jan 20;10(1):739. doi: 10.1038/s41598-020-57723-2. PubMed
Reversible expansion of pancreatic islet progenitors derived from human induced pluripotent stem cells. Tanaka A, Watanabe A, Nakano Y, Matsumoto M, Okazaki Y, Miyajima A. Genes Cells. 2020 May;25(5):302-311. doi: 10.1111/gtc.12759. Epub 2020 Mar 6. PubMed
Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi004-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene. Zhang J, Wei L, Chen D, Feng L, Wu C, Wang R, Li X, Liu H. Stem Cell Res. 2020 Apr;44:101741. doi: 10.1016/j.scr.2020.101741. Epub 2020 Feb 20. PubMed
Generation of induced pluripotent stem cell line (CSUXHi002-A) from a patient with spinocerebellar ataxia type 1. He L, Zhao H, Li S, Han X, Chen Z, Wang C, Tian C, Tang F, Huang R, Lin Z, Li Z, Tang B, Jiang H. Stem Cell Res. 2020 May;45:101816. doi: 10.1016/j.scr.2020.101816. Epub 2020 Apr 21. PubMed
Generation of an induced pluripotent stem cell line from chorionic villi of a Patau syndrome spontaneous abortion. Long P, Liu Z, Wu B, Chen J, Sun C, Wang F, Huang Y, Chen H, Li Q, Ma Y. Stem Cell Res. 2020 May;45:101789. doi: 10.1016/j.scr.2020.101789. Epub 2020 Apr 22. PubMed
Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi001-A) from a healthy male individual. Zhang J, Wei L, Wang R, Li X, Liu Z. Stem Cell Res. 2020 May;45:101809. doi: 10.1016/j.scr.2020.101809. Epub 2020 Apr 24. PubMed
Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936. Toombs J, Panther L, Ornelas L, Liu C, Gomez E, Martin-Ibanez R, Cox SR, Ritchie SJ, Harris SE, Taylor A, Redmond P, Russ TC, Murphy L, Cooper JD, Burr K, Selvaraj BT, Browne C, Svendsen CN, Cowley SA, Deary IJ, Chandran S, Spires-Jones TL, Sareen D. Stem Cell Res. 2020 Jul;46:101851. doi: 10.1016/j.scr.2020.101851. Epub 2020 May 20. PubMed
Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi002-A) from a patient with spinocerebellar ataxia type 3. Wei L, Zhang J, Chen D, Feng L, Wu C, Wang R, Li X. Stem Cell Res. 2020 Aug;47:101898. doi: 10.1016/j.scr.2020.101898. Epub 2020 Jun 29. PubMed
Generation of an integration-free induced pluripotent stem cell (iPSC) line (ZZUNEUi005-A) from a Wilson's disease patient harboring a homozygous Pro992Leu mutation in ATP7B gene. Wei L, Zhang J, Chen D, Feng L, Wu C, Wang R, Li X. Stem Cell Res. 2020 Jul 15;47:101909. doi: 10.1016/j.scr.2020.101909. PubMed
Generation and characterization of iPSC lines (BGUi004-A, BGUi005-A) from two identical twins with polyalanine expansion in the paired-like homeobox 2B (PHOX2B) gene. Falik D, Rabinski T, Zlotnik D, Eshel R, Zorsky M, Garin-Shkolnik T, Ofir R, Adato A, Ashkenazi A, Vatine GD. Stem Cell Res. 2020 Oct;48:101955. doi: 10.1016/j.scr.2020.101955. Epub 2020 Aug 14. PubMed
Generation of iPSC lines from two (BGUi002-A and BGUi003-A) homozygous p450 oxidoreductase-deficient patients and from one (BGUi001-A) heterozygous healthy family relative. Zlotnik D, Rabinski T, Ofir R, Hershkovitz E, Vatine GD. Stem Cell Res. 2020 Oct;48:101975. doi: 10.1016/j.scr.2020.101975. Epub 2020 Sep 1. PubMed
Generation of an iPSC line (UMGWi001-B) from a patient with Floating-Harbor Syndrome (FLHS) carrying a heterozygous SRCAP mutation (p.Arg2444). Franz M, Hagenau L, Koch R, Neubauer S, Nowack B, Tzvetkova A, Jensen LR, Kuss AW. Stem Cell Res. 2020 Dec;49:102028. doi: 10.1016/j.scr.2020.102028. Epub 2020 Oct 9. PubMed
GATA6 regulates aging of human mesenchymal stem/stromal cells. Jiao H, Walczak BE, Lee MS, Lemieux ME, Li WJ. Stem Cells. 2021 Jan;39(1):62-77. doi: 10.1002/stem.3297. Epub 2020 Nov 30. PubMed
Reprogramming of two induced pluripotent stem cell lines from a heterozygous GRIN2D developmental and epileptic encephalopathy (DEE) patient (BGUi011-A) and from a healthy family relative (BGUi012-A). Rabinski T, Sagiv ST, Hausman-Kedem M, Fattal-Valevski A, Rubinstein M, Avraham KB, Vatine GD. Stem Cell Res. 2021 Mar;51:102178. doi: 10.1016/j.scr.2021.102178. Epub 2021 Jan 15. PubMed
Generation of six induced pluripotent stem cell lines from patients with amyotrophic lateral sclerosis with associated genetic mutations in either FUS or ANXA11. Hedges EC, Topp S, Shaw CE, Nishimura AL. Stem Cell Res. 2021 Apr;52:102246. doi: 10.1016/j.scr.2021.102246. Epub 2021 Feb 12. PubMed
Generation of spinocerebellar ataxia type 3 patient-derived induced pluripotent stem cell line (CSUXHi005-A) from human urine epithelial cells. He L, Han X, Zhao H, Li S, Chen Z, Wang C, Wang S, Peng L, Deng W, Li Z, Tang B, Jiang H. Stem Cell Res. 2021 May;53:102289. doi: 10.1016/j.scr.2021.102289. Epub 2021 Mar 17. PubMed
Human iPSC-derived neurons reveal early developmental alteration of neurite outgrowth in the late-occurring neurodegenerative Wolfram syndrome. Pourtoy-Brasselet S, Sciauvaud A, Boza-Moran MG, Cailleret M, Jarrige M, Polveche H, Polentes J, Chevet E, Martinat C, Peschanski M, Aubry L. Am J Hum Genet. 2021 Nov 4;108(11):2171-2185. doi: 10.1016/j.ajhg.2021.10.001. Epub 2021 Oct 25. PubMed

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