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ptfLC3 Citations (250)

Plasmid Article: Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3.
Kimura S, Noda T, Yoshimori T Autophagy. 2007;3(5):452-60.
PubMed Journal

Articles Citing ptfLC3

Identification of PTPsigma as an autophagic phosphatase. Martin KR, Xu Y, Looyenga BD, Davis RJ, Wu CL, Tremblay ML, Xu HE, MacKeigan JP. J Cell Sci. 2011 Mar 1;124(Pt 5):812-9. doi: 10.1242/jcs.080341. Epub 2011 Feb 8. PubMed
A role for autophagy during hepatic stellate cell activation. Thoen LF, Guimaraes EL, Dolle L, Mannaerts I, Najimi M, Sokal E, van Grunsven LA. J Hepatol. 2011 Dec;55(6):1353-60. doi: 10.1016/j.jhep.2011.07.010. Epub 2011 Jul 29. PubMed
Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome. Tumbarello DA, Waxse BJ, Arden SD, Bright NA, Kendrick-Jones J, Buss F. Nat Cell Biol. 2012 Oct;14(10):1024-35. doi: 10.1038/ncb2589. Epub 2012 Sep 30. PubMed
Lysosome vacuolation disrupts the completion of autophagy during norephedrine exposure in SH-SY5Y human neuroblastoma cells. Funakoshi T, Aki T, Unuma K, Uemura K. Brain Res. 2013 Jan 15;1490:9-22. doi: 10.1016/j.brainres.2012.10.056. Epub 2012 Nov 2. PubMed
Delphinidin induces autolysosome as well as autophagosome formation and delphinidin-induced autophagy exerts a cell protective role. Tsuyuki S, Fukui S, Watanabe A, Akune S, Tanabe M, Yoshida K. J Biochem Mol Toxicol. 2012 Nov;26(11):445-53. doi: 10.1002/jbt.21443. Epub 2012 Nov 5. PubMed
Computational model for autophagic vesicle dynamics in single cells. Martin KR, Barua D, Kauffman AL, Westrate LM, Posner RG, Hlavacek WS, Mackeigan JP. Autophagy. 2013 Jan;9(1):74-92. doi: 10.4161/auto.22532. Epub 2012 Nov 29. PubMed
Zinc oxide nanoparticle induced autophagic cell death and mitochondrial damage via reactive oxygen species generation. Yu KN, Yoon TJ, Minai-Tehrani A, Kim JE, Park SJ, Jeong MS, Ha SW, Lee JK, Kim JS, Cho MH. Toxicol In Vitro. 2013 Jun;27(4):1187-95. doi: 10.1016/j.tiv.2013.02.010. Epub 2013 Feb 28. PubMed
The thiazole derivative CPTH6 impairs autophagy. Ragazzoni Y, Desideri M, Gabellini C, De Luca T, Carradori S, Secci D, Nescatelli R, Candiloro A, Condello M, Meschini S, Del Bufalo D, Trisciuoglio D. Cell Death Dis. 2013 Mar 7;4:e524. doi: 10.1038/cddis.2013.53. PubMed
Removal of the BH4 domain from Bcl-2 protein triggers an autophagic process that impairs tumor growth. Trisciuoglio D, De Luca T, Desideri M, Passeri D, Gabellini C, Scarpino S, Liang C, Orlandi A, Del Bufalo D. Neoplasia. 2013 Mar;15(3):315-27. PubMed
Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death. Martin S, Harper CB, May LM, Coulson EJ, Meunier FA, Osborne SL. PLoS One. 2013;8(3):e60152. doi: 10.1371/journal.pone.0060152. Epub 2013 Mar 27. PubMed
Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy. Yang Y, Fiskus W, Yong B, Atadja P, Takahashi Y, Pandita TK, Wang HG, Bhalla KN. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):6841-6. doi: 10.1073/pnas.1217692110. Epub 2013 Apr 8. PubMed
Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS). Korvatska O, Strand NS, Berndt JD, Strovas T, Chen DH, Leverenz JB, Kiianitsa K, Mata IF, Karakoc E, Greenup JL, Bonkowski E, Chuang J, Moon RT, Eichler EE, Nickerson DA, Zabetian CP, Kraemer BC, Bird TD, Raskind WH. Hum Mol Genet. 2013 Aug 15;22(16):3259-68. doi: 10.1093/hmg/ddt180. Epub 2013 Apr 16. PubMed
Spatiotemporally controlled induction of autophagy-mediated lysosome turnover. Hung YH, Chen LM, Yang JY, Yang WY. Nat Commun. 2013;4:2111. doi: 10.1038/ncomms3111. PubMed
Autophagy defect is associated with low glucose-induced apoptosis in 661W photoreceptor cells. Balmer D, Emery M, Andreux P, Auwerx J, Ginet V, Puyal J, Schorderet DF, Roduit R. PLoS One. 2013 Sep 16;8(9):e74162. doi: 10.1371/journal.pone.0074162. eCollection 2013. PubMed
The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death. Qiao S, Tao S, Rojo de la Vega M, Park SL, Vonderfecht AA, Jacobs SL, Zhang DD, Wondrak GT. Autophagy. 2013 Dec;9(12):2087-102. doi: 10.4161/auto.26506. Epub 2013 Oct 8. PubMed
Phospholipase D2 mediates survival signaling through direct regulation of Akt in glioblastoma cells. Bruntz RC, Taylor HE, Lindsley CW, Brown HA. J Biol Chem. 2014 Jan 10;289(2):600-16. doi: 10.1074/jbc.M113.532978. Epub 2013 Nov 20. PubMed
Autophagy activation reduces renal tubular injury induced by urinary proteins. Liu WJ, Luo MN, Tan J, Chen W, Huang LZ, Yang C, Pan Q, Li B, Liu HF. Autophagy. 2014 Feb;10(2):243-56. doi: 10.4161/auto.27004. Epub 2013 Nov 26. PubMed
Calcineurin suppresses AMPK-dependent cytoprotective autophagy in cardiomyocytes under oxidative stress. He H, Liu X, Lv L, Liang H, Leng B, Zhao D, Zhang Y, Du Z, Chen X, Li S, Lu Y, Shan H. Cell Death Dis. 2014 Jan 16;5:e997. doi: 10.1038/cddis.2013.533. PubMed
Involvement of autophagy in hypoxic-excitotoxic neuronal death. Ginet V, Spiehlmann A, Rummel C, Rudinskiy N, Grishchuk Y, Luthi-Carter R, Clarke PG, Truttmann AC, Puyal J. Autophagy. 2014 May;10(5):846-60. doi: 10.4161/auto.28264. Epub 2014 Mar 11. PubMed
Antagonism of tumoral prolactin receptor promotes autophagy-related cell death. Wen Y, Zand B, Ozpolat B, Szczepanski MJ, Lu C, Yuca E, Carroll AR, Alpay N, Bartholomeusz C, Tekedereli I, Kang Y, Rupaimoole R, Pecot CV, Dalton HJ, Hernandez A, Lokshin A, Lutgendorf SK, Liu J, Hittelman WN, Chen WY, Lopez-Berestein G, Szajnik M, Ueno NT, Coleman RL, Sood AK. Cell Rep. 2014 Apr 24;7(2):488-500. doi: 10.1016/j.celrep.2014.03.009. Epub 2014 Apr 3. PubMed
Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction. Fang EF, Scheibye-Knudsen M, Brace LE, Kassahun H, SenGupta T, Nilsen H, Mitchell JR, Croteau DL, Bohr VA. Cell. 2014 May 8;157(4):882-96. doi: 10.1016/j.cell.2014.03.026. PubMed
Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib. Goodall ML, Wang T, Martin KR, Kortus MG, Kauffman AL, Trent JM, Gately S, MacKeigan JP. Autophagy. 2014 Jun;10(6):1120-36. doi: 10.4161/auto.28594. PubMed
FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation. Dunlop EA, Seifan S, Claessens T, Behrends C, Kamps MA, Rozycka E, Kemp AJ, Nookala RK, Blenis J, Coull BJ, Murray JT, van Steensel MA, Wilkinson S, Tee AR. Autophagy. 2014 Oct 1;10(10):1749-60. doi: 10.4161/auto.29640. Epub 2014 Jul 22. PubMed
Abeta1-42 monomers or oligomers have different effects on autophagy and apoptosis. Guglielmotto M, Monteleone D, Piras A, Valsecchi V, Tropiano M, Ariano S, Fornaro M, Vercelli A, Puyal J, Arancio O, Tabaton M, Tamagno E. Autophagy. 2014 Oct 1;10(10):1827-43. doi: 10.4161/auto.30001. Epub 2014 Aug 12. PubMed
WW domain of BAG3 is required for the induction of autophagy in glioma cells. Merabova N, Sariyer IK, Saribas AS, Knezevic T, Gordon J, Turco MC, Rosati A, Weaver M, Landry J, Khalili K. J Cell Physiol. 2015 Apr;230(4):831-41. doi: 10.1002/jcp.24811. PubMed
Nutrient-sensing nuclear receptors coordinate autophagy. Lee JM, Wagner M, Xiao R, Kim KH, Feng D, Lazar MA, Moore DD. Nature. 2014 Dec 4;516(7529):112-5. doi: 10.1038/nature13961. Epub 2014 Nov 12. PubMed
Immunotherapy targeting folate receptor induces cell death associated with autophagy in ovarian cancer. Wen Y, Graybill WS, Previs RA, Hu W, Ivan C, Mangala LS, Zand B, Nick AM, Jennings NB, Dalton HJ, Sehgal V, Ram P, Lee JS, Vivas-Mejia PE, Coleman RL, Sood AK. Clin Cancer Res. 2015 Jan 15;21(2):448-59. doi: 10.1158/1078-0432.CCR-14-1578. Epub 2014 Nov 21. PubMed
Inhibition of autophagy as a new means of improving chemotherapy efficiency in high-LC3B triple-negative breast cancers. Lefort S, Joffre C, Kieffer Y, Givel AM, Bourachot B, Zago G, Bieche I, Dubois T, Meseure D, Vincent-Salomon A, Camonis J, Mechta-Grigoriou F. Autophagy. 2014;10(12):2122-42. doi: 10.4161/15548627.2014.981788. PubMed
Autophagic flux without a block differentiates varicella-zoster virus infection from herpes simplex virus infection. Buckingham EM, Carpenter JE, Jackson W, Zerboni L, Arvin AM, Grose C. Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):256-61. doi: 10.1073/pnas.1417878112. Epub 2014 Dec 22. PubMed
FBXW7-Induced MTOR Degradation Forces Autophagy to Counteract Persistent Prion Infection. Xu Y, Tian C, Sun J, Zhang J, Ren K, Fan XY, Wang K, Wang H, Yan YE, Chen C, Shi Q, Dong XP. Mol Neurobiol. 2015 Jan 13. PubMed
beta-Cyclodextrin-threaded biocleavable polyrotaxanes ameliorate impaired autophagic flux in Niemann-Pick type C disease. Tamura A, Yui N. J Biol Chem. 2015 Apr 10;290(15):9442-54. doi: 10.1074/jbc.M115.636803. Epub 2015 Feb 24. PubMed
The multikinase inhibitor Sorafenib enhances glycolysis and synergizes with glycolysis blockade for cancer cell killing. Tesori V, Piscaglia AC, Samengo D, Barba M, Bernardini C, Scatena R, Pontoglio A, Castellini L, Spelbrink JN, Maulucci G, Puglisi MA, Pani G, Gasbarrini A. Sci Rep. 2015 Mar 17;5:9149. doi: 10.1038/srep09149. PubMed
Endothelial uncoupling protein 2 regulates mitophagy and pulmonary hypertension during intermittent hypoxia. Haslip M, Dostanic I, Huang Y, Zhang Y, Russell KS, Jurczak MJ, Mannam P, Giordano F, Erzurum SC, Lee PJ. Arterioscler Thromb Vasc Biol. 2015 May;35(5):1166-78. doi: 10.1161/ATVBAHA.114.304865. Epub 2015 Mar 26. PubMed
Autophagy induction by silibinin positively contributes to its anti-metastatic capacity via AMPK/mTOR pathway in renal cell carcinoma. Li F, Ma Z, Guan Z, Chen Y, Wu K, Guo P, Wang X, He D, Zeng J. Int J Mol Sci. 2015 Apr 15;16(4):8415-29. doi: 10.3390/ijms16048415. PubMed
Proximity Ligation In situ Assay is a Powerful Tool to Monitor Specific ATG Protein Interactions following Autophagy Induction. Gauthier T, Claude-Taupin A, Delage-Mourroux R, Boyer-Guittaut M, Hervouet E. PLoS One. 2015 Jun 2;10(6):e0128701. doi: 10.1371/journal.pone.0128701. eCollection 2015. PubMed
AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia. Ruozi G, Bortolotti F, Falcione A, Dal Ferro M, Ukovich L, Macedo A, Zentilin L, Filigheddu N, Gortan Cappellari G, Baldini G, Zweyer M, Barazzoni R, Graziani A, Zacchigna S, Giacca M. Nat Commun. 2015 Jun 11;6:7388. doi: 10.1038/ncomms8388. PubMed
Ethambutol induces impaired autophagic flux and apoptosis in the rat retina. Huang SP, Chien JY, Tsai RK. Dis Model Mech. 2015 Aug 1;8(8):977-87. doi: 10.1242/dmm.019737. Epub 2015 Jun 18. PubMed
The Cytotoxicity of Elderberry Ribosome-Inactivating Proteins Is Not Solely Determined by Their Protein Translation Inhibition Activity. Shang C, Chen Q, Dell A, Haslam SM, De Vos WH, Van Damme EJ. PLoS One. 2015 Jul 6;10(7):e0132389. doi: 10.1371/journal.pone.0132389. eCollection 2015. PubMed
Differing roles of autophagy in HIV-associated neurocognitive impairment and encephalitis with implications for morphine co-exposure. Dever SM, Rodriguez M, Lapierre J, Costin BN, El-Hage N. Front Microbiol. 2015 Jul 6;6:653. doi: 10.3389/fmicb.2015.00653. eCollection 2015. PubMed
KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation. Brooks CR, Yeung MY, Brooks YS, Chen H, Ichimura T, Henderson JM, Bonventre JV. EMBO J. 2015 Oct 1;34(19):2441-64. doi: 10.15252/embj.201489838. Epub 2015 Aug 17. PubMed
G9a Inhibition Induces Autophagic Cell Death via AMPK/mTOR Pathway in Bladder Transitional Cell Carcinoma. Li F, Zeng J, Gao Y, Guan Z, Ma Z, Shi Q, Du C, Jia J, Xu S, Wang X, Chang L, He D, Guo P. PLoS One. 2015 Sep 23;10(9):e0138390. doi: 10.1371/journal.pone.0138390. eCollection 2015. PubMed
Quantitative analysis of autophagic flux by confocal pH-imaging of autophagic intermediates. Maulucci G, Chiarpotto M, Papi M, Samengo D, Pani G, De Spirito M. Autophagy. 2015 Oct 3;11(10):1905-16. doi: 10.1080/15548627.2015.1084455. PubMed
MicroRNA 17-5p regulates autophagy in Mycobacterium tuberculosis-infected macrophages by targeting Mcl-1 and STAT3. Kumar R, Sahu SK, Kumar M, Jana K, Gupta P, Gupta UD, Kundu M, Basu J. Cell Microbiol. 2015 Oct 29. doi: 10.1111/cmi.12540. PubMed
Glycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1alpha-c-Jun N-terminal kinase cascade in non-small cell lung cancer cells. Tang ZH, Zhang LL, Li T, Lu JH, Ma DL, Leung CH, Chen XP, Jiang HL, Wang YT, Lu JJ. Oncotarget. 2015 Dec 22;6(41):43911-26. doi: 10.18632/oncotarget.6084. PubMed
Autophagy of metallothioneins prevents TNF-induced oxidative stress and toxicity in hepatoma cells. Ullio C, Brunk UT, Urani C, Melchioretto P, Bonelli G, Baccino FM, Autelli R. Autophagy. 2015;11(12):2184-98. doi: 10.1080/15548627.2015.1106662. PubMed
Deficiency of Neuronal p38alpha MAPK Attenuates Amyloid Pathology in Alzheimer Disease Mouse and Cell Models through Facilitating Lysosomal Degradation of BACE1. Schnoder L, Hao W, Qin Y, Liu S, Tomic I, Liu X, Fassbender K, Liu Y. J Biol Chem. 2016 Jan 29;291(5):2067-79. doi: 10.1074/jbc.M115.695916. Epub 2015 Dec 9. PubMed
2,2'-dipyridyl induces pexophagy. Jin A, Lee JN, Kim MS, Kwak S, Kim SJ, Song K, Choe SK, Park R. Biochem Biophys Res Commun. 2016 Jan 22;469(4):941-7. doi: 10.1016/j.bbrc.2015.12.098. Epub 2015 Dec 23. PubMed
Imaging organelle transport in primary hippocampal neurons treated with amyloid-beta oligomers. Gan KJ, Silverman MA. Methods Cell Biol. 2016;131:425-51. doi: 10.1016/bs.mcb.2015.06.012. Epub 2015 Sep 2. PubMed
Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A. Kim N, Kim MJ, Sung PS, Bae YC, Shin EC, Yoo JY. Nat Commun. 2016 Feb 12;7:10631. doi: 10.1038/ncomms10631. PubMed
C/EBPbeta regulates sensitivity to bortezomib in prostate cancer cells by inducing REDD1 and autophagosome-lysosome fusion. Barakat DJ, Mendonca J, Barberi T, Zhang J, Kachhap SK, Paz-Priel I, Friedman AD. Cancer Lett. 2016 May 28;375(1):152-61. doi: 10.1016/j.canlet.2016.03.005. Epub 2016 Mar 8. PubMed
Autophagy-related cell death by pan-histone deacetylase inhibition in liver cancer. Di Fazio P, Waldegger P, Jabari S, Lingelbach S, Montalbano R, Ocker M, Slater EP, Bartsch DK, Illig R, Neureiter D, Wissniowski TT. Oncotarget. 2016 Apr 5. doi: 10.18632/oncotarget.8585. PubMed
Skeletal muscle action of estrogen receptor alpha is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. Sci Transl Med. 2016 Apr 13;8(334):334ra54. doi: 10.1126/scitranslmed.aad3815. PubMed
Persistent activation of autophagy in kidney tubular cells promotes renal interstitial fibrosis during unilateral ureteral obstruction. Livingston MJ, Ding HF, Huang S, Hill JA, Yin XM, Dong Z. Autophagy. 2016 Jun 2;12(6):976-98. doi: 10.1080/15548627.2016.1166317. Epub 2016 Apr 28. PubMed
Role of TFEB-driven autophagy regulation in pancreatic cancer treatment. Klein K, Werner K, Teske C, Schenk M, Giese T, Weitz J, Welsch T. Int J Oncol. 2016 Jul;49(1):164-72. doi: 10.3892/ijo.2016.3505. Epub 2016 May 5. PubMed
TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells. Ra EA, Lee TA, Won Kim S, Park A, Choi HJ, Jang I, Kang S, Hee Cheon J, Cho JW, Eun Lee J, Lee S, Park B. Nat Commun. 2016 May 24;7:11726. doi: 10.1038/ncomms11726. PubMed
Stellettin B Induces G1 Arrest, Apoptosis and Autophagy in Human Non-small Cell Lung Cancer A549 Cells via Blocking PI3K/Akt/mTOR Pathway. Wang R, Zhang Q, Peng X, Zhou C, Zhong Y, Chen X, Qiu Y, Jin M, Gong M, Kong D. Sci Rep. 2016 May 31;6:27071. doi: 10.1038/srep27071. PubMed
Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells. Li X, Zhu F, Jiang J, Sun C, Zhong Q, Shen M, Wang X, Tian R, Shi C, Xu M, Peng F, Guo X, Hu J, Ye D, Wang M, Qin R. Autophagy. 2016 Sep;12(9):1521-37. doi: 10.1080/15548627.2016.1191722. Epub 2016 Jun 16. PubMed
Rab7 induces clearance of alpha-synuclein aggregates. Dinter E, Saridaki T, Nippold M, Plum S, Diederichs L, Komnig D, Fensky L, May C, Marcus K, Voigt A, Schulz JB, Falkenburger BH. J Neurochem. 2016 Sep;138(5):758-74. doi: 10.1111/jnc.13712. Epub 2016 Aug 4. PubMed
Cocaine induces astrocytosis through ER stress-mediated activation of autophagy. Periyasamy P, Guo ML, Buch S. Autophagy. 2016 Aug 2;12(8):1310-29. doi: 10.1080/15548627.2016.1183844. Epub 2016 Jun 23. PubMed
Wild-type rabies virus induces autophagy in human and mouse neuroblastoma cell lines. Peng J, Zhu S, Hu L, Ye P, Wang Y, Tian Q, Mei M, Chen H, Guo X. Autophagy. 2016 Oct 2;12(10):1704-1720. Epub 2016 Jul 27. PubMed
Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy. Bartlett JJ, Trivedi PC, Yeung P, Kienesberger PC, Pulinilkunnil T. Biochem J. 2016 Nov 1;473(21):3769-3789. Epub 2016 Aug 3. PubMed
Lactate Dehydrogenase B Controls Lysosome Activity and Autophagy in Cancer. Brisson L, Banski P, Sboarina M, Dethier C, Danhier P, Fontenille MJ, Van Hee VF, Vazeille T, Tardy M, Falces J, Bouzin C, Porporato PE, Frederick R, Michiels C, Copetti T, Sonveaux P. Cancer Cell. 2016 Sep 12;30(3):418-431. doi: 10.1016/j.ccell.2016.08.005. PubMed
LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes. Hubert V, Peschel A, Langer B, Groger M, Rees A, Kain R. Biol Open. 2016 Oct 15;5(10):1516-1529. doi: 10.1242/bio.018648. PubMed
Lithium improves cell viability in psychosine-treated MO3.13 human oligodendrocyte cell line via autophagy activation. Del Grosso A, Antonini S, Angella L, Tonazzini I, Signore G, Cecchini M. J Neurosci Res. 2016 Nov;94(11):1246-60. doi: 10.1002/jnr.23910. PubMed
Suppression of Sestrins in aging and osteoarthritic cartilage: dysfunction of an important stress defense mechanism. Shen T, Alvarez-Garcia O, Li Y, Olmer M, Lotz MK. Osteoarthritis Cartilage. 2017 Feb;25(2):287-296. doi: 10.1016/j.joca.2016.09.017. Epub 2016 Sep 29. PubMed
Short chain fatty acids induce UCP2-mediated autophagy in hepatic cells. Iannucci LF, Sun J, Singh BK, Zhou J, Kaddai VA, Lanni A, Yen PM, Sinha RA. Biochem Biophys Res Commun. 2016 Nov 18;480(3):461-467. doi: 10.1016/j.bbrc.2016.10.072. Epub 2016 Oct 20. PubMed
Autophagy activated by tuberin/mTOR/p70S6K suppression is a protective mechanism against local anaesthetics neurotoxicity. Xiong J, Kong Q, Dai L, Ma H, Cao X, Liu L, Ding Z. J Cell Mol Med. 2016 Nov 15. doi: 10.1111/jcmm.13003. PubMed
ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins. Villarroya-Beltri C, Baixauli F, Mittelbrunn M, Fernandez-Delgado I, Torralba D, Moreno-Gonzalo O, Baldanta S, Enrich C, Guerra S, Sanchez-Madrid F. Nat Commun. 2016 Nov 24;7:13588. doi: 10.1038/ncomms13588. PubMed
Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation. Tripathi M, Zhang CW, Singh BK, Sinha RA, Moe KT, DeSilva DA, Yen PM. Cell Death Dis. 2016 Dec 8;7(12):e2513. doi: 10.1038/cddis.2016.374. PubMed
SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages. Shi B, Huang QQ, Birkett R, Doyle R, Dorfleutner A, Stehlik C, He C, Pope RM. Autophagy. 2016 Dec 8:1-17. doi: 10.1080/15548627.2016.1261238. PubMed
PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Ruf S, Heberle AM, Langelaar-Makkinje M, Gelino S, Wilkinson D, Gerbeth C, Schwarz JJ, Holzwarth B, Warscheid B, Meisinger C, van Vugt MA, Baumeister R, Hansen M, Thedieck K. Autophagy. 2017 Mar 4;13(3):486-505. doi: 10.1080/15548627.2016.1263781. Epub 2017 Jan 19. PubMed
Mevastatin blockade of autolysosome maturation stimulates LBH589-induced cell death in triple-negative breast cancer cells. Lin Z, Zhang Z, Jiang X, Kou X, Bao Y, Liu H, Sun F, Ling S, Qin N, Jiang L, Yang Y. Oncotarget. 2017 Mar 14;8(11):17833-17848. doi: 10.18632/oncotarget.14868. PubMed
The amino acid metabolite homocysteine activates mTORC1 to inhibit autophagy and form abnormal proteins in human neurons and mice. Khayati K, Antikainen H, Bonder EM, Weber GF, Kruger WD, Jakubowski H, Dobrowolski R. FASEB J. 2017 Feb;31(2):598-609. doi: 10.1096/fj.201600915R. Epub 2016 Oct 25. PubMed
Viability of primary cultured podocytes is associated with extracellular high glucose-dependent autophagy downregulation. Audzeyenka I, Rogacka D, Piwkowska A, Angielski S, Jankowski M. Mol Cell Biochem. 2017 Jun;430(1-2):11-19. doi: 10.1007/s11010-017-2949-5. Epub 2017 Feb 24. PubMed
Osimertinib induces autophagy and apoptosis via reactive oxygen species generation in non-small cell lung cancer cells. Tang ZH, Cao WX, Su MX, Chen X, Lu JJ. Toxicol Appl Pharmacol. 2017 Apr 15;321:18-26. doi: 10.1016/j.taap.2017.02.017. Epub 2017 Feb 22. PubMed
Intra-articular lentivirus-mediated gene therapy targeting CRACM1 for the treatment of collagen-induced arthritis. Liu S, Kiyoi T, Takemasa E, Maeyama K. J Pharmacol Sci. 2017 Mar;133(3):130-138. doi: 10.1016/j.jphs.2017.02.001. Epub 2017 Feb 11. PubMed
Prototype foamy virus elicits complete autophagy involving the ER stress-related UPR pathway. Yuan P, Dong L, Cheng Q, Wang S, Li Z, Sun Y, Han S, Yin J, Peng B, He X, Liu W. Retrovirology. 2017 Mar 7;14(1):16. doi: 10.1186/s12977-017-0341-x. PubMed
A novel autophagy modulator 6-Bio ameliorates SNCA/alpha-synuclein toxicity. Suresh SN, Chavalmane AK, Dj V, Yarreiphang H, Rai S, Paul A, Clement JP, Alladi PA, Manjithaya R. Autophagy. 2017 Jul 3;13(7):1221-1234. doi: 10.1080/15548627.2017.1302045. Epub 2017 Mar 28. PubMed
Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells. Basit F, van Oppen LM, Schockel L, Bossenbroek HM, van Emst-de Vries SE, Hermeling JC, Grefte S, Kopitz C, Heroult M, Hgm Willems P, Koopman WJ. Cell Death Dis. 2017 Mar 30;8(3):e2716. doi: 10.1038/cddis.2017.133. PubMed
Endophilin B2 facilitates endosome maturation in response to growth factor stimulation, autophagy induction, and influenza A virus infection. Serfass JM, Takahashi Y, Zhou Z, Kawasawa YI, Liu Y, Tsotakos N, Young MM, Tang Z, Yang L, Atkinson JM, Chroneos ZC, Wang HG. J Biol Chem. 2017 Jun 16;292(24):10097-10111. doi: 10.1074/jbc.M117.792747. Epub 2017 Apr 28. PubMed
p62/sequestosome 1 in human colorectal carcinoma as a potent prognostic predictor associated with cell proliferation. Nakayama S, Karasawa H, Suzuki T, Yabuuchi S, Takagi K, Aizawa T, Onodera Y, Nakamura Y, Watanabe M, Fujishima F, Yoshida H, Morikawa T, Sase T, Naitoh T, Unno M, Sasano H. Cancer Med. 2017 Jun;6(6):1264-1274. doi: 10.1002/cam4.1093. Epub 2017 May 23. PubMed
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