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MSCV JMJD3 mutant Citations (6)

Originally described in: Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3.
Sen GL, Webster DE, Barragan DI, Chang HY, Khavari PA Genes Dev. 2008 Jul 15. 22(14):1865-70.
PubMed Journal

Articles Citing MSCV JMJD3 mutant

UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia. Benyoucef A, Palii CG, Wang C, Porter CJ, Chu A, Dai F, Tremblay V, Rakopoulos P, Singh K, Huang S, Pflumio F, Hebert J, Couture JF, Perkins TJ, Ge K, Dilworth FJ, Brand M. Genes Dev. 2016 Mar 1;30(5):508-21. doi: 10.1101/gad.276790.115. PubMed
Regulation of the JMJD3 (KDM6B) histone demethylase in glioblastoma stem cells by STAT3. Sherry-Lynes MM, Sengupta S, Kulkarni S, Cochran BH. PLoS One. 2017 Apr 6;12(4):e0174775. doi: 10.1371/journal.pone.0174775. eCollection 2017. PubMed
Notch-effector CSL promotes squamous cell carcinoma by repressing histone demethylase KDM6B. Al Labban D, Jo SH, Ostano P, Saglietti C, Bongiovanni M, Panizzon R, Dotto GP. J Clin Invest. 2018 Jun 1;128(6):2581-2599. doi: 10.1172/JCI96915. Epub 2018 May 14. PubMed
Histone demethylase KDM6B has an anti-tumorigenic function in neuroblastoma by promoting differentiation. Yang L, Zha Y, Ding J, Ye B, Liu M, Yan C, Dong Z, Cui H, Ding HF. Oncogenesis. 2019 Jan 4;8(1):3. doi: 10.1038/s41389-018-0112-0. PubMed
KDM6B promotes PARthanatos via suppression of O6-methylguanine DNA methyltransferase repair and sustained checkpoint response. Yang M, Wang C, Zhou M, Bao L, Wang Y, Kumar A, Xing C, Luo W, Wang Y. Nucleic Acids Res. 2022 Jun 24;50(11):6313-6331. doi: 10.1093/nar/gkac471. PubMed
Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters. van Gils N, Verhagen HJMP, Broux M, Martianez T, Denkers F, Vermue E, Rutten A, Csikos T, Demeyer S, Cil M, Al M, Cools J, Janssen JJWM, Ossenkoppele GJ, Menezes RX, Smit L. iScience. 2022 Aug 25;25(9):105013. doi: 10.1016/j.isci.2022.105013. eCollection 2022 Sep 16. PubMed

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